Cargando…

Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study

BACKGROUND: Many parents continue to reject caudal block since they worry about a rare neurological consequence that may happen. A parenteral surrogate is sought because it can induce recovery with features such as local analgesia. OBJECTIVES: To compare the efficacy and safety of intravenous dexmed...

Descripción completa

Detalles Bibliográficos
Autores principales: Omara, Amany Faheem, Elzohry, Alaa Ali, Abdelrahman, Ahmed Fetouh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363365/
https://www.ncbi.nlm.nih.gov/pubmed/37489170
http://dx.doi.org/10.5812/aapm-130623
_version_ 1785076610298281984
author Omara, Amany Faheem
Elzohry, Alaa Ali
Abdelrahman, Ahmed Fetouh
author_facet Omara, Amany Faheem
Elzohry, Alaa Ali
Abdelrahman, Ahmed Fetouh
author_sort Omara, Amany Faheem
collection PubMed
description BACKGROUND: Many parents continue to reject caudal block since they worry about a rare neurological consequence that may happen. A parenteral surrogate is sought because it can induce recovery with features such as local analgesia. OBJECTIVES: To compare the efficacy and safety of intravenous dexmedetomidine versus caudal and general anesthesia (GA) in children undergoing hypospadias surgery repair. METHODS: A randomized prospective study was conducted on 135 pediatric patients scheduled for hypospadias repair surgery in the hospital affiliated to Tanta University. The participants were divided into a control group (Group C) receiving GA, a caudal group receiving caudal block after GA, and a dexmedetomidine group (Group D) receiving intravenous dexmedetomidine after GA. The postoperative modified objective pain score (MOPS), the total pethidine received in the first 24 h postoperatively, and complications were recorded. RESULTS: The patients receiving GA required a significantly higher pethidine dose than the other two groups without a significant difference between caudal and dexmedetomidine. The patients receiving dexmedetomidine were extubated significantly later than patients in the other two groups. Regarding the MOPS score, there was a significant difference between Group C and the other two groups 30 minutes and one hour after operation regarding movements, posture, and agitation. Moreover, a significantly larger number of patients developed tachycardia in Group C compared to the other groups. CONCLUSIONS: With the caudal block, the benefits of smooth emergency can be obtained by intravenous dexmedetomidine; however, it had less analgesic efficacy in the pediatric patients undergoing hypospadias repair surgery.
format Online
Article
Text
id pubmed-10363365
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Brieflands
record_format MEDLINE/PubMed
spelling pubmed-103633652023-07-24 Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study Omara, Amany Faheem Elzohry, Alaa Ali Abdelrahman, Ahmed Fetouh Anesth Pain Med Research Article BACKGROUND: Many parents continue to reject caudal block since they worry about a rare neurological consequence that may happen. A parenteral surrogate is sought because it can induce recovery with features such as local analgesia. OBJECTIVES: To compare the efficacy and safety of intravenous dexmedetomidine versus caudal and general anesthesia (GA) in children undergoing hypospadias surgery repair. METHODS: A randomized prospective study was conducted on 135 pediatric patients scheduled for hypospadias repair surgery in the hospital affiliated to Tanta University. The participants were divided into a control group (Group C) receiving GA, a caudal group receiving caudal block after GA, and a dexmedetomidine group (Group D) receiving intravenous dexmedetomidine after GA. The postoperative modified objective pain score (MOPS), the total pethidine received in the first 24 h postoperatively, and complications were recorded. RESULTS: The patients receiving GA required a significantly higher pethidine dose than the other two groups without a significant difference between caudal and dexmedetomidine. The patients receiving dexmedetomidine were extubated significantly later than patients in the other two groups. Regarding the MOPS score, there was a significant difference between Group C and the other two groups 30 minutes and one hour after operation regarding movements, posture, and agitation. Moreover, a significantly larger number of patients developed tachycardia in Group C compared to the other groups. CONCLUSIONS: With the caudal block, the benefits of smooth emergency can be obtained by intravenous dexmedetomidine; however, it had less analgesic efficacy in the pediatric patients undergoing hypospadias repair surgery. Brieflands 2023-02-06 /pmc/articles/PMC10363365/ /pubmed/37489170 http://dx.doi.org/10.5812/aapm-130623 Text en Copyright © 2023, Author(s) https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
spellingShingle Research Article
Omara, Amany Faheem
Elzohry, Alaa Ali
Abdelrahman, Ahmed Fetouh
Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study
title Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study
title_full Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study
title_fullStr Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study
title_full_unstemmed Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study
title_short Comparison of Caudal Block and Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery: A Prospective, Randomized, Double-blinded Clinical Study
title_sort comparison of caudal block and dexmedetomidine infusion in pediatric patients undergoing hypospadias repair surgery: a prospective, randomized, double-blinded clinical study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363365/
https://www.ncbi.nlm.nih.gov/pubmed/37489170
http://dx.doi.org/10.5812/aapm-130623
work_keys_str_mv AT omaraamanyfaheem comparisonofcaudalblockanddexmedetomidineinfusioninpediatricpatientsundergoinghypospadiasrepairsurgeryaprospectiverandomizeddoubleblindedclinicalstudy
AT elzohryalaaali comparisonofcaudalblockanddexmedetomidineinfusioninpediatricpatientsundergoinghypospadiasrepairsurgeryaprospectiverandomizeddoubleblindedclinicalstudy
AT abdelrahmanahmedfetouh comparisonofcaudalblockanddexmedetomidineinfusioninpediatricpatientsundergoinghypospadiasrepairsurgeryaprospectiverandomizeddoubleblindedclinicalstudy