B-cell immunity and vaccine induced antibody protection reveal the inefficacy of current vaccination schedule in infants with perinatal HIV-infection in Mozambique, Africa

BACKGROUND: Despite antiretroviral treatment (ART), immune dysfunction persists in children with perinatal HIV infection (HEI). Here we investigated the impact of HIV status on maternal antibody (Ab) passage, long-term vaccine induced immunity and B-cell maturation. METHODS: 46 HIV Exposed Uninfecte...

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Detalles Bibliográficos
Autores principales: Cotugno, Nicola, Pallikkuth, Suresh, Sanna, Marco, Dinh, Vinh, de Armas, Lesley, Rinaldi, Stefano, Davis, Sheldon, Linardos, Giulia, Pascucci, Giuseppe Rubens, Pahwa, Rajendra, Sitoe, Nadia, Vaz, Paula, Rossi, Paolo, Lain, Maria Grazia, Palma, Paolo, Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363429/
https://www.ncbi.nlm.nih.gov/pubmed/37406590
http://dx.doi.org/10.1016/j.ebiom.2023.104666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363429/
https://www.ncbi.nlm.nih.gov/pubmed/37406590
http://dx.doi.org/10.1016/j.ebiom.2023.104666

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