Endothelial Gata6 deletion reduces monocyte recruitment and proinflammatory macrophage formation and attenuates atherosclerosis through Cmpk2-Nlrp3 pathways

Endothelial dysfunction results in chronic vascular inflammation, which is critical for the development of atherosclerotic diseases. Transcription factor Gata6 has been reported to regulate vascular endothelial cell activation and inflammation in vitro. Here, we aimed to explore the roles and mechan...

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Detalles Bibliográficos
Autores principales: Wu, Wenrun, Bao, Wenzhen, Chen, Xiaoli, Lu, Yushi, Fang, Ji, Liu, Jiwen, Peng, Sheng, Pi, Jingjiang, Tomlinson, Brian, Chan, Paul, Zhang, Qi, Zhang, Lin, Liu, Zhongmin, Liu, Jie, Zhang, Yuzhen, Zhuang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363430/
https://www.ncbi.nlm.nih.gov/pubmed/37339559
http://dx.doi.org/10.1016/j.redox.2023.102775

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