Vascular protection afforded by zinc supplementation in human coronary artery smooth muscle cells mediated by NRF2 signaling under hypoxia/reoxygenation

Zinc (Zn) has antioxidant, anti-inflammatory and anti-proliferative actions, with Zn dysregulation associated with coronary ischemia/reperfusion injury and smooth muscle cell dysfunction. As the majority of studies concerning Zn have been conducted under non-physiological hyperoxic conditions, we co...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Smith, Matthew J., Griffiths, Alexander, Morrell, Alexander, Chapple, Sarah J., Siow, Richard C.M., Stewart, Theodora, Maret, Wolfgang, Mann, Giovanni E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363453/
https://www.ncbi.nlm.nih.gov/pubmed/37315344
http://dx.doi.org/10.1016/j.redox.2023.102777

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