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PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have attracted attention in the field of regenerative medicine due to their potential ability to repair damaged hearts. However, the immature phenotype of these cells limits their clinical application. Cardiomyocyte maturation is...

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Detalles Bibliográficos
Autores principales: Liu, Huiwen, Sun, Yanting, Xu, Hao, Tan, Bin, Yi, Qin, Tian, Jie, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363588/
https://www.ncbi.nlm.nih.gov/pubmed/37492732
http://dx.doi.org/10.1016/j.gendis.2022.08.023