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A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature

A Solitary Fibrous Tumor (SFT) is a rare, aggressive, and metastasis- and recurrence- prone mesenchymal tumor. In this case report and review, we describe a rare instance of intracranial SFT, discovered for the first time. It was discovered in 2008 and following total surgical removal, the pathology...

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Autores principales: Gao, YiMeng, Xu, Yan, Xie, RuiZhi, Shen, YouBi, Xue, DaoJin, Zhen, Zheng, Lu, JingJing, Huang, Tao, Peng, ZiZhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363678/
https://www.ncbi.nlm.nih.gov/pubmed/37492853
http://dx.doi.org/10.3389/fneur.2023.1201964
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author Gao, YiMeng
Xu, Yan
Xie, RuiZhi
Shen, YouBi
Xue, DaoJin
Zhen, Zheng
Lu, JingJing
Huang, Tao
Peng, ZiZhuang
author_facet Gao, YiMeng
Xu, Yan
Xie, RuiZhi
Shen, YouBi
Xue, DaoJin
Zhen, Zheng
Lu, JingJing
Huang, Tao
Peng, ZiZhuang
author_sort Gao, YiMeng
collection PubMed
description A Solitary Fibrous Tumor (SFT) is a rare, aggressive, and metastasis- and recurrence- prone mesenchymal tumor. In this case report and review, we describe a rare instance of intracranial SFT, discovered for the first time. It was discovered in 2008 and following total surgical removal, the pathology was categorized as hemangiopericytoma cell tumor (HPC) at the time by WHO tumor criteria. An imaging review 8 months after surgery revealed a tumor recurrence: combined radiation and gamma-knife therapy was continued throughout this time. The tumor did not metastasis until June 2018 when it presented in the pancreas with ruptured bleeding and a postoperative pathology was suggestive of SFT. Fortunately, the patient is still alive nearly 3 years after the 2020 surgery, after staged surgical resection and combined multimedia therapy, with no imaging or clinical evidence of a recurrent intracranial primary lesions. To our knowledge, there is no previous record of using a combined treatment modality for Intracranial Solitary Fibrous Tumor (ISFT). Combined with an account of the patient's experience, we empirically describe a combined approach with a preference for gross-total resection (GTR), supplemented by multimodal assistance with stereotactic (radiotherapy), gamma knife (GK), molecular targeting, and immunization for patients admitted acutely, with accurate preoperative identification and aggressive management after intraoperative case response to maximize treatment of recurrent ISFT and improve prognosis. We recommend multimodal management for SFT with prolonged-term recurrence and metastases, both for the control benefits of GTR, RT, or GK for local recurrence and for the positive prognosis of targeted and immune metastases.
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spelling pubmed-103636782023-07-25 A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature Gao, YiMeng Xu, Yan Xie, RuiZhi Shen, YouBi Xue, DaoJin Zhen, Zheng Lu, JingJing Huang, Tao Peng, ZiZhuang Front Neurol Neurology A Solitary Fibrous Tumor (SFT) is a rare, aggressive, and metastasis- and recurrence- prone mesenchymal tumor. In this case report and review, we describe a rare instance of intracranial SFT, discovered for the first time. It was discovered in 2008 and following total surgical removal, the pathology was categorized as hemangiopericytoma cell tumor (HPC) at the time by WHO tumor criteria. An imaging review 8 months after surgery revealed a tumor recurrence: combined radiation and gamma-knife therapy was continued throughout this time. The tumor did not metastasis until June 2018 when it presented in the pancreas with ruptured bleeding and a postoperative pathology was suggestive of SFT. Fortunately, the patient is still alive nearly 3 years after the 2020 surgery, after staged surgical resection and combined multimedia therapy, with no imaging or clinical evidence of a recurrent intracranial primary lesions. To our knowledge, there is no previous record of using a combined treatment modality for Intracranial Solitary Fibrous Tumor (ISFT). Combined with an account of the patient's experience, we empirically describe a combined approach with a preference for gross-total resection (GTR), supplemented by multimodal assistance with stereotactic (radiotherapy), gamma knife (GK), molecular targeting, and immunization for patients admitted acutely, with accurate preoperative identification and aggressive management after intraoperative case response to maximize treatment of recurrent ISFT and improve prognosis. We recommend multimodal management for SFT with prolonged-term recurrence and metastases, both for the control benefits of GTR, RT, or GK for local recurrence and for the positive prognosis of targeted and immune metastases. Frontiers Media S.A. 2023-07-10 /pmc/articles/PMC10363678/ /pubmed/37492853 http://dx.doi.org/10.3389/fneur.2023.1201964 Text en Copyright © 2023 Gao, Xu, Xie, Shen, Xue, Zhen, Lu, Huang and Peng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Gao, YiMeng
Xu, Yan
Xie, RuiZhi
Shen, YouBi
Xue, DaoJin
Zhen, Zheng
Lu, JingJing
Huang, Tao
Peng, ZiZhuang
A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
title A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
title_full A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
title_fullStr A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
title_full_unstemmed A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
title_short A rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
title_sort rare case of intracranial solitary fibrous tumor that is still alive after multiple surgical resections: a case report and review of the literature
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363678/
https://www.ncbi.nlm.nih.gov/pubmed/37492853
http://dx.doi.org/10.3389/fneur.2023.1201964
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