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Bioactive peptides derived from Radix Angelicae sinensis inhibit ferroptosis in HT22 cells through direct Keap1–Nrf2 PPI inhibition
The development of natural peptides as direct Kelch-like ECH-associated protein 1 (Keap1)–nuclear factor erythroid2-related factor 2 (Nrf2) protein–protein interaction (PPI) inhibitors for antioxidant and anti-ferroptotic purposes has attracted increasing interest from chemists. Radix Angelicae sine...
Autores principales: | Chen, Ban, Ouyang, Xiaojian, Cheng, Chunfeng, Chen, Dongfeng, Su, Jiangtao, Hu, Yuchen, Li, Xican |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363710/ https://www.ncbi.nlm.nih.gov/pubmed/37492506 http://dx.doi.org/10.1039/d3ra04057g |
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