Blood cell traits’ GWAS loci colocalization with variation in PU.1 genomic occupancy prioritizes causal noncoding regulatory variants

Genome-wide association studies (GWASs) have uncovered numerous trait-associated loci across the human genome, most of which are located in noncoding regions, making interpretation difficult. Moreover, causal variants are hard to statistically fine-map at many loci because of widespread linkage dise...

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Detalles Bibliográficos
Autores principales: Jeong, Raehoon, Bulyk, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363807/
https://www.ncbi.nlm.nih.gov/pubmed/37492098
http://dx.doi.org/10.1016/j.xgen.2023.100327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363807/
https://www.ncbi.nlm.nih.gov/pubmed/37492098
http://dx.doi.org/10.1016/j.xgen.2023.100327

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