Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy

Morbidity and mortality associated with radiation-induced secondary malignancies (RISMs) have shifted treatment paradigms to minimize or eliminate radiation from treatment regimens. In this case, a 48-year-old woman was diagnosed with Hodgkin lymphoma (HL) and treated with radiotherapy in 2000. In 2...

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Autores principales: White, Donnell, Sadough Shahmirzadi, Maryam, Boulmay, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363863/
https://www.ncbi.nlm.nih.gov/pubmed/37480256
http://dx.doi.org/10.1177/23247096231188251
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author White, Donnell
Sadough Shahmirzadi, Maryam
Boulmay, Brian
author_facet White, Donnell
Sadough Shahmirzadi, Maryam
Boulmay, Brian
author_sort White, Donnell
collection PubMed
description Morbidity and mortality associated with radiation-induced secondary malignancies (RISMs) have shifted treatment paradigms to minimize or eliminate radiation from treatment regimens. In this case, a 48-year-old woman was diagnosed with Hodgkin lymphoma (HL) and treated with radiotherapy in 2000. In 2018, she was diagnosed with ductal carcinoma in situ (DCIS) of the right breast and treated with a mastectomy. Soon after, she developed triple-negative invasive ductal carcinoma (IDC) in her reconstructed breast. The patient underwent a left lumpectomy, and pathology showed ER–/PR–/HER2+ IDC. This patient’s multi-phenotypic DCIS and IDC presentation are suspected to be RISM due to her previous HL treatment regimen.
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spelling pubmed-103638632023-07-25 Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy White, Donnell Sadough Shahmirzadi, Maryam Boulmay, Brian J Investig Med High Impact Case Rep Case Report Morbidity and mortality associated with radiation-induced secondary malignancies (RISMs) have shifted treatment paradigms to minimize or eliminate radiation from treatment regimens. In this case, a 48-year-old woman was diagnosed with Hodgkin lymphoma (HL) and treated with radiotherapy in 2000. In 2018, she was diagnosed with ductal carcinoma in situ (DCIS) of the right breast and treated with a mastectomy. Soon after, she developed triple-negative invasive ductal carcinoma (IDC) in her reconstructed breast. The patient underwent a left lumpectomy, and pathology showed ER–/PR–/HER2+ IDC. This patient’s multi-phenotypic DCIS and IDC presentation are suspected to be RISM due to her previous HL treatment regimen. SAGE Publications 2023-07-22 /pmc/articles/PMC10363863/ /pubmed/37480256 http://dx.doi.org/10.1177/23247096231188251 Text en © 2023 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
White, Donnell
Sadough Shahmirzadi, Maryam
Boulmay, Brian
Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy
title Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy
title_full Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy
title_fullStr Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy
title_full_unstemmed Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy
title_short Multi-Phenotypic Breast Cancer Post-Radiotherapy for Hodgkin Lymphoma: A Case of Secondary Malignancy
title_sort multi-phenotypic breast cancer post-radiotherapy for hodgkin lymphoma: a case of secondary malignancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363863/
https://www.ncbi.nlm.nih.gov/pubmed/37480256
http://dx.doi.org/10.1177/23247096231188251
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AT boulmaybrian multiphenotypicbreastcancerpostradiotherapyforhodgkinlymphomaacaseofsecondarymalignancy

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