Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

A primary obstacle in translating genetic associations with disease into therapeutic strategies is elucidating the cellular programs affected by genetic risk variants and effector genes. Here, we introduce LipocyteProfiler, a cardiometabolic-disease-oriented high-content image-based profiling tool t...

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Detalles Bibliográficos
Autores principales: Laber, Samantha, Strobel, Sophie, Mercader, Josep M., Dashti, Hesam, dos Santos, Felipe R.C., Kubitz, Phil, Jackson, Maya, Ainbinder, Alina, Honecker, Julius, Agrawal, Saaket, Garborcauskas, Garrett, Stirling, David R., Leong, Aaron, Figueroa, Katherine, Sinnott-Armstrong, Nasa, Kost-Alimova, Maria, Deodato, Giacomo, Harney, Alycen, Way, Gregory P., Saadat, Alham, Harken, Sierra, Reibe-Pal, Saskia, Ebert, Hannah, Zhang, Yixin, Calabuig-Navarro, Virtu, McGonagle, Elizabeth, Stefek, Adam, Dupuis, Josée, Cimini, Beth A., Hauner, Hans, Udler, Miriam S., Carpenter, Anne E., Florez, Jose C., Lindgren, Cecilia, Jacobs, Suzanne B.R., Claussnitzer, Melina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363917/
https://www.ncbi.nlm.nih.gov/pubmed/37492099
http://dx.doi.org/10.1016/j.xgen.2023.100346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363917/
https://www.ncbi.nlm.nih.gov/pubmed/37492099
http://dx.doi.org/10.1016/j.xgen.2023.100346

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