New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project

Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays. For NGTxCs, DNA is not the primary target, and the p...

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Detalles Bibliográficos
Autores principales: Audebert, Marc, Assmann, Ann-Sophie, Azqueta, Amaya, Babica, Pavel, Benfenati, Emilio, Bortoli, Sylvie, Bouwman, Peter, Braeuning, Albert, Burgdorf, Tanja, Coumoul, Xavier, Debizet, Kloé, Dusinska, Maria, Ertych, Norman, Fahrer, Jörg, Fetz, Verena, Le Hégarat, Ludovic, López de Cerain, Adela, Heusinkveld, Harm J., Hogeveen, Kevin, Jacobs, Miriam N., Luijten, Mirjam, Raitano, Giuseppa, Recoules, Cynthia, Rundén-Pran, Elise, Saleh, Mariam, Sovadinová, Iva, Stampar, Martina, Thibol, Lea, Tomkiewicz, Céline, Vettorazzi, Ariane, Van de Water, Bob, El Yamani, Naouale, Zegura, Bojana, Oelgeschläger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364052/
https://www.ncbi.nlm.nih.gov/pubmed/37492623
http://dx.doi.org/10.3389/ftox.2023.1220998

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