Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone

Immune checkpoint inhibitors highlight the importance of anticancer immunity. However, their clinical utility and safety are limited by the low response rates and adverse effects. We focused on progesterone (P4), a hormone produced by the placenta during pregnancy, because it has multiple biological...

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Detalles Bibliográficos
Autores principales: Kametani, Yoshie, Ito, Ryoji, Ohshima, Shino, Manabe, Yoshiyuki, Ohno, Yusuke, Shimizu, Tomoka, Yamada, Soga, Katano, Nagi, Kirigaya, Daiki, Ito, Keita, Matsumoto, Takuya, Tsuda, Banri, Kashiwagi, Hirofumi, Goto, Yumiko, Yasuda, Atsushi, Maeki, Masatoshi, Tokeshi, Manabu, Seki, Toshiro, Fukase, Koichi, Mikami, Mikio, Ando, Kiyoshi, Ishimoto, Hitoshi, Shiina, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364058/
https://www.ncbi.nlm.nih.gov/pubmed/37492571
http://dx.doi.org/10.3389/fimmu.2023.1173728

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