Sox, Fox, and Lmx1b binding sites differentially regulate a Gdf5-Associated regulatory region during elbow development

Introduction: The articulating ends of limb bones have precise morphology and asymmetry that ensures proper joint function. Growth differentiation factor 5 (Gdf5) is a secreted morphogen involved in cartilage and bone development that contributes to the architecture of developing joints. Dysregulati...

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Detalles Bibliográficos
Autores principales: Yeboah, Ruth-Love, Pira, Charmaine U., Shankel, Matthew, Cooper, Allen M., Haro, Endika, Ly, Van-Dai, Wysong, Kenrick, Zhang, Michael, Sandoval, Nicole, Oberg, Kerby C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364121/
https://www.ncbi.nlm.nih.gov/pubmed/37492222
http://dx.doi.org/10.3389/fcell.2023.1215406

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