Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering

The stimuli-responsive nanofibers prepared by electrospinning have become an ideal stimuli-responsive material due to their large specific surface area and porosity, which can respond extremely quickly to external environmental incitement. As an intelligent drug delivery platform, stimuli-responsive...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Kai, Li, Yonghui, Li, Youbin, Tan, Yinfeng, Liu, Yingshuo, Pan, Weisan, Tan, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364421/
https://www.ncbi.nlm.nih.gov/pubmed/37488582
http://dx.doi.org/10.1186/s12951-023-01987-z
_version_ 1785076842125852672
author Chen, Kai
Li, Yonghui
Li, Youbin
Tan, Yinfeng
Liu, Yingshuo
Pan, Weisan
Tan, Guoxin
author_facet Chen, Kai
Li, Yonghui
Li, Youbin
Tan, Yinfeng
Liu, Yingshuo
Pan, Weisan
Tan, Guoxin
author_sort Chen, Kai
collection PubMed
description The stimuli-responsive nanofibers prepared by electrospinning have become an ideal stimuli-responsive material due to their large specific surface area and porosity, which can respond extremely quickly to external environmental incitement. As an intelligent drug delivery platform, stimuli-responsive nanofibers can efficiently load drugs and then be stimulated by specific conditions (light, temperature, magnetic field, ultrasound, pH or ROS, etc.) to achieve slow, on-demand or targeted release, showing great potential in areas such as drug delivery, tumor therapy, wound dressing, and tissue engineering. Therefore, this paper reviews the recent trends of stimuli-responsive electrospun nanofibers as intelligent drug delivery platforms in the field of biomedicine.
format Online
Article
Text
id pubmed-10364421
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-103644212023-07-25 Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering Chen, Kai Li, Yonghui Li, Youbin Tan, Yinfeng Liu, Yingshuo Pan, Weisan Tan, Guoxin J Nanobiotechnology Review The stimuli-responsive nanofibers prepared by electrospinning have become an ideal stimuli-responsive material due to their large specific surface area and porosity, which can respond extremely quickly to external environmental incitement. As an intelligent drug delivery platform, stimuli-responsive nanofibers can efficiently load drugs and then be stimulated by specific conditions (light, temperature, magnetic field, ultrasound, pH or ROS, etc.) to achieve slow, on-demand or targeted release, showing great potential in areas such as drug delivery, tumor therapy, wound dressing, and tissue engineering. Therefore, this paper reviews the recent trends of stimuli-responsive electrospun nanofibers as intelligent drug delivery platforms in the field of biomedicine. BioMed Central 2023-07-24 /pmc/articles/PMC10364421/ /pubmed/37488582 http://dx.doi.org/10.1186/s12951-023-01987-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Chen, Kai
Li, Yonghui
Li, Youbin
Tan, Yinfeng
Liu, Yingshuo
Pan, Weisan
Tan, Guoxin
Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
title Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
title_full Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
title_fullStr Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
title_full_unstemmed Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
title_short Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
title_sort stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364421/
https://www.ncbi.nlm.nih.gov/pubmed/37488582
http://dx.doi.org/10.1186/s12951-023-01987-z
work_keys_str_mv AT chenkai stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering
AT liyonghui stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering
AT liyoubin stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering
AT tanyinfeng stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering
AT liuyingshuo stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering
AT panweisan stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering
AT tanguoxin stimuliresponsiveelectrospunnanofibersfordrugdeliverycancertherapywounddressingandtissueengineering

Ejemplares similares