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Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service

BACKGROUND: Since 1999, the Scottish National Service for Thoracoabdominal Aneurysms has offered repair of thoracoabdominal aneurysms (TAAAs) to a population of 5.5 million people. The open operation most commonly performed by the service is the extent IV TAAA repair. METHODS: All extent IV open TAA...

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Autores principales: Forsythe, Rachael O, Eng, Calvin, Roy, Chloe, Cafferkey, John, Clinch, Darja, Ventham, Nicholas, Tambyraja, Andrew L, Burns, Phillipa J, Falah, Orwa, Chalmers, Roderick T A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364699/
https://www.ncbi.nlm.nih.gov/pubmed/35716129
http://dx.doi.org/10.1093/bjs/znac049
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author Forsythe, Rachael O
Eng, Calvin
Roy, Chloe
Cafferkey, John
Clinch, Darja
Ventham, Nicholas
Tambyraja, Andrew L
Burns, Phillipa J
Falah, Orwa
Chalmers, Roderick T A
author_facet Forsythe, Rachael O
Eng, Calvin
Roy, Chloe
Cafferkey, John
Clinch, Darja
Ventham, Nicholas
Tambyraja, Andrew L
Burns, Phillipa J
Falah, Orwa
Chalmers, Roderick T A
author_sort Forsythe, Rachael O
collection PubMed
description BACKGROUND: Since 1999, the Scottish National Service for Thoracoabdominal Aneurysms has offered repair of thoracoabdominal aneurysms (TAAAs) to a population of 5.5 million people. The open operation most commonly performed by the service is the extent IV TAAA repair. METHODS: All extent IV open TAAA repairs performed at the Scottish National Service for TAAAs from June 1999 until April 2021 were evaluated for clinical features, technical details, and clinical outcomes. The primary outcome measure was 30-day mortality; secondary outcomes included short-term (90 days, 6 months, 1 and 2 years) and long-term (5 and 10 years) survival, perioperative complications, and reintervention. Survival was assessed using Kaplan–Meier analysis. RESULTS: Some 248 patients underwent extent IV TAAA repair, with elective surgery in 204 (82.3 per cent). A totally abdominal transperitoneal approach was used for all patients, with a median visceral ischaemia time of 40 (i.q.r. 35–48) min. Overall, 18 patients (7.3 per cent) died within 30 days. The proportion of patients surviving at 90 days, 6 months, 1, 2, 5, and 10 years was 0.91, 0.90, 0.89, 0.85, 0.72, and 0.41, respectively. Ten patients (4.0 per cent) required a reintervention while in hospital, four (1.6 per cent) experienced permanent spinal cord ischaemia, 19 (7.9 per cent) required temporary renal replacement therapy (RRT), and four (1.6 per cent) required permanent RRT. CONCLUSION: Open extent IV TAAA repair performed in a high-volume national centre is associated with favourable short- and long-term survival, and acceptable complication rates.
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spelling pubmed-103646992023-07-31 Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service Forsythe, Rachael O Eng, Calvin Roy, Chloe Cafferkey, John Clinch, Darja Ventham, Nicholas Tambyraja, Andrew L Burns, Phillipa J Falah, Orwa Chalmers, Roderick T A Br J Surg Original Article BACKGROUND: Since 1999, the Scottish National Service for Thoracoabdominal Aneurysms has offered repair of thoracoabdominal aneurysms (TAAAs) to a population of 5.5 million people. The open operation most commonly performed by the service is the extent IV TAAA repair. METHODS: All extent IV open TAAA repairs performed at the Scottish National Service for TAAAs from June 1999 until April 2021 were evaluated for clinical features, technical details, and clinical outcomes. The primary outcome measure was 30-day mortality; secondary outcomes included short-term (90 days, 6 months, 1 and 2 years) and long-term (5 and 10 years) survival, perioperative complications, and reintervention. Survival was assessed using Kaplan–Meier analysis. RESULTS: Some 248 patients underwent extent IV TAAA repair, with elective surgery in 204 (82.3 per cent). A totally abdominal transperitoneal approach was used for all patients, with a median visceral ischaemia time of 40 (i.q.r. 35–48) min. Overall, 18 patients (7.3 per cent) died within 30 days. The proportion of patients surviving at 90 days, 6 months, 1, 2, 5, and 10 years was 0.91, 0.90, 0.89, 0.85, 0.72, and 0.41, respectively. Ten patients (4.0 per cent) required a reintervention while in hospital, four (1.6 per cent) experienced permanent spinal cord ischaemia, 19 (7.9 per cent) required temporary renal replacement therapy (RRT), and four (1.6 per cent) required permanent RRT. CONCLUSION: Open extent IV TAAA repair performed in a high-volume national centre is associated with favourable short- and long-term survival, and acceptable complication rates. Oxford University Press 2022-06-18 /pmc/articles/PMC10364699/ /pubmed/35716129 http://dx.doi.org/10.1093/bjs/znac049 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of BJS Society Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Article
Forsythe, Rachael O
Eng, Calvin
Roy, Chloe
Cafferkey, John
Clinch, Darja
Ventham, Nicholas
Tambyraja, Andrew L
Burns, Phillipa J
Falah, Orwa
Chalmers, Roderick T A
Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service
title Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service
title_full Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service
title_fullStr Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service
title_full_unstemmed Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service
title_short Open extent IV thoracoabdominal aneurysm repair: 22-year experience of the Scottish National Service
title_sort open extent iv thoracoabdominal aneurysm repair: 22-year experience of the scottish national service
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364699/
https://www.ncbi.nlm.nih.gov/pubmed/35716129
http://dx.doi.org/10.1093/bjs/znac049
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