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A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery

BACKGROUND: Laparoscopy has been widely adopted in elective abdominal surgery but is still sparsely used in emergency settings. The study investigated the effect of laparoscopic emergency surgery using a population database. METHODS: Data for all patients from December 2013 to November 2018 were ret...

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Autores principales: Pucher, P H, Mackenzie, H, Tucker, V, Mercer, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364898/
https://www.ncbi.nlm.nih.gov/pubmed/33724351
http://dx.doi.org/10.1093/bjs/znab048
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author Pucher, P H
Mackenzie, H
Tucker, V
Mercer, S J
author_facet Pucher, P H
Mackenzie, H
Tucker, V
Mercer, S J
author_sort Pucher, P H
collection PubMed
description BACKGROUND: Laparoscopy has been widely adopted in elective abdominal surgery but is still sparsely used in emergency settings. The study investigated the effect of laparoscopic emergency surgery using a population database. METHODS: Data for all patients from December 2013 to November 2018 were retrieved from the NELA national database of emergency laparotomy for England and Wales. Laparoscopically attempted cases were matched 2 : 1 with open cases for propensity score derived from a logistic regression model for surgical approach; included co-variates were age, gender, predicted mortality risk, and diagnostic, procedural and surgeon variables. Groups were compared for mortality. Secondary endpoints were blood loss and duration of hospital stay. RESULTS: Of 116 920 patients considered, 17 040 underwent laparoscopic surgery. The most common procedures were colectomy, adhesiolysis, washout and perforated ulcer repair. Of these, 11 753 were matched exactly to 23 506 patients who had open surgery. Laparoscopically attempted surgery was associated with lower mortality (6.0 versus 9.1 per cent, P < 0.001), blood loss (less than 100 ml, 64.4 versus 52.0 per cent, P < 0.001), and duration of hospital stay (median 8 (i.q.r. 5–14) versus 10 (7–18) days, P < 0.001). Similar trends were seen when comparing only successful laparoscopic cases with open surgery, and also when comparing cases converted to open surgery with open surgery. CONCLUSION: In appropriately selected patients, laparoscopy is associated with superior outcomes compared with open emergency surgery.
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spelling pubmed-103648982023-07-31 A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery Pucher, P H Mackenzie, H Tucker, V Mercer, S J Br J Surg Original Articles BACKGROUND: Laparoscopy has been widely adopted in elective abdominal surgery but is still sparsely used in emergency settings. The study investigated the effect of laparoscopic emergency surgery using a population database. METHODS: Data for all patients from December 2013 to November 2018 were retrieved from the NELA national database of emergency laparotomy for England and Wales. Laparoscopically attempted cases were matched 2 : 1 with open cases for propensity score derived from a logistic regression model for surgical approach; included co-variates were age, gender, predicted mortality risk, and diagnostic, procedural and surgeon variables. Groups were compared for mortality. Secondary endpoints were blood loss and duration of hospital stay. RESULTS: Of 116 920 patients considered, 17 040 underwent laparoscopic surgery. The most common procedures were colectomy, adhesiolysis, washout and perforated ulcer repair. Of these, 11 753 were matched exactly to 23 506 patients who had open surgery. Laparoscopically attempted surgery was associated with lower mortality (6.0 versus 9.1 per cent, P < 0.001), blood loss (less than 100 ml, 64.4 versus 52.0 per cent, P < 0.001), and duration of hospital stay (median 8 (i.q.r. 5–14) versus 10 (7–18) days, P < 0.001). Similar trends were seen when comparing only successful laparoscopic cases with open surgery, and also when comparing cases converted to open surgery with open surgery. CONCLUSION: In appropriately selected patients, laparoscopy is associated with superior outcomes compared with open emergency surgery. Oxford University Press 2021-03-16 /pmc/articles/PMC10364898/ /pubmed/33724351 http://dx.doi.org/10.1093/bjs/znab048 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of BJS Society Ltd. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Pucher, P H
Mackenzie, H
Tucker, V
Mercer, S J
A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
title A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
title_full A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
title_fullStr A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
title_full_unstemmed A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
title_short A national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
title_sort national propensity score-matched analysis of emergency laparoscopic versus open abdominal surgery
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10364898/
https://www.ncbi.nlm.nih.gov/pubmed/33724351
http://dx.doi.org/10.1093/bjs/znab048
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