Cargando…

Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide

Visceral hemangiosarcomas (HSA) are rare in cats and typically associated with aggressive biologic behavior and poor prognosis. A 4‐year‐old male neutered domestic shorthair cat was presented with a 3‐month history of hematuria and stranguria; ultrasonography identified a large bladder mass. Complet...

Descripción completa

Detalles Bibliográficos
Autores principales: McNally, Abigail, Rossanese, Matteo, Suárez‐Bonnet, Alejandro, Hardas, Alexandros, Yale, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365030/
https://www.ncbi.nlm.nih.gov/pubmed/37381579
http://dx.doi.org/10.1111/jvim.16750
Descripción
Sumario:Visceral hemangiosarcomas (HSA) are rare in cats and typically associated with aggressive biologic behavior and poor prognosis. A 4‐year‐old male neutered domestic shorthair cat was presented with a 3‐month history of hematuria and stranguria; ultrasonography identified a large bladder mass. Complete excision was achieved by partial cystectomy. Histopathology and immunohistochemistry for von Willebrand factor confirmed HSA. The cat was treated using adjuvant cyclophosphamide, thalidomide, and meloxicam for 8 months. Abdominal ultrasonography repeated at 2 months and computed tomography repeated at 5 and 19 months after diagnosis showed no evidence of local recurrence or metastasis. The cat was alive at last follow‐up (896 days). Although the cat described in this report experienced a more favorable prognosis compared to other visceral HSA locations, additional cases are needed to further understand the biological behavior of bladder HSAs and guide treatment decisions.