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Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran

BACKGROUND: The heart is the first fully developed organ in early pregnancy, especially in the first trimester of pregnancy, so any factor that contributes to heart failure is life-threatening. Thus, it is important to identify the risk and preventive factors related to this disease and to provide a...

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Autores principales: Amini-Rarani, Mostafa, Karimi, Salah Eddin, SoleimanvandiAzar, Neda, Nosratabadi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365085/
https://www.ncbi.nlm.nih.gov/pubmed/37492609
http://dx.doi.org/10.3389/fped.2023.1170743
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author Amini-Rarani, Mostafa
Karimi, Salah Eddin
SoleimanvandiAzar, Neda
Nosratabadi, Mehdi
author_facet Amini-Rarani, Mostafa
Karimi, Salah Eddin
SoleimanvandiAzar, Neda
Nosratabadi, Mehdi
author_sort Amini-Rarani, Mostafa
collection PubMed
description BACKGROUND: The heart is the first fully developed organ in early pregnancy, especially in the first trimester of pregnancy, so any factor that contributes to heart failure is life-threatening. Thus, it is important to identify the risk and preventive factors related to this disease and to provide a scientific basis for the control, prevention, management and treatment of Child with Congenital Heart Diseases (CHD). OBJECTIVES: As the etiology of CHD is multifactorial, to identify the risk and preventive factors, this study aimed to investigate the factors related to CHD in Tehran, Iran. METHODS: The present case-control study was performed on 600 people including 200 mothers of children with CHD. Simple random sampling was performed in 2020. The control group was matched with the case group, and the data were analyzed by SPSS software at a significance level of 0.5. RESULTS: The results showed that low socioeconomic status, low education, history of abortion, smoking, alcohol consumption are risk factors, and consumption of folic acid, and prenatal care are the protective factors against CHD. CONCLUSION: According to the findings, our emphasis should be on preventive strategies, education of mothers and public health experts on the need for folic acid and pregnancy care, and cessation or reduction of alcohol and tobacco use, especially in families with low socioeconomic status and low level of education.
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spelling pubmed-103650852023-07-25 Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran Amini-Rarani, Mostafa Karimi, Salah Eddin SoleimanvandiAzar, Neda Nosratabadi, Mehdi Front Pediatr Pediatrics BACKGROUND: The heart is the first fully developed organ in early pregnancy, especially in the first trimester of pregnancy, so any factor that contributes to heart failure is life-threatening. Thus, it is important to identify the risk and preventive factors related to this disease and to provide a scientific basis for the control, prevention, management and treatment of Child with Congenital Heart Diseases (CHD). OBJECTIVES: As the etiology of CHD is multifactorial, to identify the risk and preventive factors, this study aimed to investigate the factors related to CHD in Tehran, Iran. METHODS: The present case-control study was performed on 600 people including 200 mothers of children with CHD. Simple random sampling was performed in 2020. The control group was matched with the case group, and the data were analyzed by SPSS software at a significance level of 0.5. RESULTS: The results showed that low socioeconomic status, low education, history of abortion, smoking, alcohol consumption are risk factors, and consumption of folic acid, and prenatal care are the protective factors against CHD. CONCLUSION: According to the findings, our emphasis should be on preventive strategies, education of mothers and public health experts on the need for folic acid and pregnancy care, and cessation or reduction of alcohol and tobacco use, especially in families with low socioeconomic status and low level of education. Frontiers Media S.A. 2023-07-03 /pmc/articles/PMC10365085/ /pubmed/37492609 http://dx.doi.org/10.3389/fped.2023.1170743 Text en © 2023 Amini-Rarani, Karimi, SoleimanvandiAzar and Nosratabadi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Amini-Rarani, Mostafa
Karimi, Salah Eddin
SoleimanvandiAzar, Neda
Nosratabadi, Mehdi
Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran
title Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran
title_full Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran
title_fullStr Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran
title_full_unstemmed Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran
title_short Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in Iran
title_sort risk and protective factors related to having a child with congenital heart diseases (chd): a case-control study in iran
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365085/
https://www.ncbi.nlm.nih.gov/pubmed/37492609
http://dx.doi.org/10.3389/fped.2023.1170743
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