Gene identification and RNAi-silencing of p62/SQSTM1 in the vector Rhodnius prolixus reveals a high degree of sequence conservation but no apparent deficiency-related phenotypes in vitellogenic females

Autophagy and the ubiquitin-proteasome system (UPS) are important cellular mechanisms that coordinate protein degradation essential for proteostasis. P62/SQSTM1 is a receptor cargo protein able to deliver ubiquitinated targets to the proteasome proteolytic complex and/or to the autophagosome. In the...

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Detalles Bibliográficos
Autores principales: Pereira, Jéssica, Santos-Araujo, Samara, Bomfim, Larissa, Gondim, Katia Calp, Majerowicz, David, Pane, Attilio, Ramos, Isabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365311/
https://www.ncbi.nlm.nih.gov/pubmed/37486954
http://dx.doi.org/10.1371/journal.pone.0287488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365311/
https://www.ncbi.nlm.nih.gov/pubmed/37486954
http://dx.doi.org/10.1371/journal.pone.0287488

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