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Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran

INTRODUCTION: COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. MATERIALS AND METHODS: This historical cohort study evaluated the survival time of hospitalized children (1 month–18 years old) with COVID-19 admitted from M...

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Autores principales: Shamsi, Farimah, Karimi, Mehran, Nafei, Zahra, Akbarian, Elahe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365916/
https://www.ncbi.nlm.nih.gov/pubmed/37492855
http://dx.doi.org/10.1155/2023/5205188
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author Shamsi, Farimah
Karimi, Mehran
Nafei, Zahra
Akbarian, Elahe
author_facet Shamsi, Farimah
Karimi, Mehran
Nafei, Zahra
Akbarian, Elahe
author_sort Shamsi, Farimah
collection PubMed
description INTRODUCTION: COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. MATERIALS AND METHODS: This historical cohort study evaluated the survival time of hospitalized children (1 month–18 years old) with COVID-19 admitted from March 2020 to August 2021 to an educational hospital in Yazd, Iran. The follow-up of patients was performed at least one month after discharge. RESULTS: From 183 hospitalized cases, 24 children were deceased. The median age of patients was 5.41, and 54.2% were male. The survival rate after one-month follow-up was 0.88, and the most significant predictors associated with survival time were the male sex, positive history of hospitalization, lymphopenia, hypoxia, and length of stay more than two weeks using Bayesian Cox regression analysis. CONCLUSION: Accurate estimation of the impact of predictors on poor outcomes may help healthcare providers use therapeutic protocols based on risk factors and healthcare requirements of each patient to improve their survival.
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spelling pubmed-103659162023-07-25 Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran Shamsi, Farimah Karimi, Mehran Nafei, Zahra Akbarian, Elahe Can J Infect Dis Med Microbiol Research Article INTRODUCTION: COVID-19 prognostic risk factors, therapeutic protocols, and clinical outcomes in pediatric cases are still under investigation. MATERIALS AND METHODS: This historical cohort study evaluated the survival time of hospitalized children (1 month–18 years old) with COVID-19 admitted from March 2020 to August 2021 to an educational hospital in Yazd, Iran. The follow-up of patients was performed at least one month after discharge. RESULTS: From 183 hospitalized cases, 24 children were deceased. The median age of patients was 5.41, and 54.2% were male. The survival rate after one-month follow-up was 0.88, and the most significant predictors associated with survival time were the male sex, positive history of hospitalization, lymphopenia, hypoxia, and length of stay more than two weeks using Bayesian Cox regression analysis. CONCLUSION: Accurate estimation of the impact of predictors on poor outcomes may help healthcare providers use therapeutic protocols based on risk factors and healthcare requirements of each patient to improve their survival. Hindawi 2023-07-17 /pmc/articles/PMC10365916/ /pubmed/37492855 http://dx.doi.org/10.1155/2023/5205188 Text en Copyright © 2023 Farimah Shamsi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shamsi, Farimah
Karimi, Mehran
Nafei, Zahra
Akbarian, Elahe
Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_full Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_fullStr Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_full_unstemmed Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_short Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran
title_sort survival and mortality in hospitalized children with covid-19: a referral center experience in yazd, iran
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10365916/
https://www.ncbi.nlm.nih.gov/pubmed/37492855
http://dx.doi.org/10.1155/2023/5205188
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