Detection of mpox virus in ambient air in a sexual health clinic

Although transmitted mainly through direct (sexual) contact, mpox virus (MPXV) can be detected in ambient air. We explored the use of air sampling for diagnosis or (genomic) surveillance of mpox in a sexual health clinic. For six out of six patients who were infected with MPXV, all four of our ambie...

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Detalles Bibliográficos
Autores principales: Raymenants, Joren, Van Gestel, Liesbeth, Coppens, Jasmine, De Block, Tessa, Bangwen, Eugene, Rutgers, Jojanneke, Hens, Matilde, De Vos, Elise, Coppens, Sandra, Keyaerts, Els, André, Emmanuel, Rezende, Antonio Mauro, Van Esbroeck, Marjan, Vercauteren, Koen, Liesenborghs, Laurens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366007/
https://www.ncbi.nlm.nih.gov/pubmed/37486383
http://dx.doi.org/10.1007/s00705-023-05837-z
Descripción
Sumario:Although transmitted mainly through direct (sexual) contact, mpox virus (MPXV) can be detected in ambient air. We explored the use of air sampling for diagnosis or (genomic) surveillance of mpox in a sexual health clinic. For six out of six patients who were infected with MPXV, all four of our ambient air PCR tests were positive. For 14 uninfected patients, PCR was positive in three ambient air samples, albeit with higher cycle threshold (C(t)) values. Genomic sequencing of samples from two positive patients showed matching sequences between air and clinical samples. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00705-023-05837-z.

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