Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure

Acute liver failure (ALF) is a severe life-threatening disease associated with the disorder of the gut-liver axis. However, the cellular characteristics of ALF in the gut and related therapeutic targets remain unexplored. Here, we utilized the D-GALN/LPS (D/L)-induced ALF model to characterize 33,21...

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Detalles Bibliográficos
Autores principales: Yin, Jie, Zhao, Ziming, Huang, Jianzheng, Xiao, Yang, Rehmutulla, Mewlude, Zhang, Biqiong, Zhang, Zijun, Xiang, Ming, Tong, Qingyi, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366100/
https://www.ncbi.nlm.nih.gov/pubmed/37488127
http://dx.doi.org/10.1038/s41421-023-00578-4

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