Cargando…

Introduction to the Monte Carlo dose engine COMPASS for BNCT

The Monte Carlo method is the most commonly used dose calculation method in the field of boron neutron capture therapy (BNCT). General-purpose Monte Carlo (MC) code (e.g., MCNP) has been used in most treatment planning systems (TPS) to calculate dose distribution, which takes overmuch time in radiot...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Wan-Bing, Chen, Jiang, Teng, Yi-Chiao, Liu, Yuan-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366114/
https://www.ncbi.nlm.nih.gov/pubmed/37488142
http://dx.doi.org/10.1038/s41598-023-38648-y
_version_ 1785077100174114816
author Zhong, Wan-Bing
Chen, Jiang
Teng, Yi-Chiao
Liu, Yuan-Hao
author_facet Zhong, Wan-Bing
Chen, Jiang
Teng, Yi-Chiao
Liu, Yuan-Hao
author_sort Zhong, Wan-Bing
collection PubMed
description The Monte Carlo method is the most commonly used dose calculation method in the field of boron neutron capture therapy (BNCT). General-purpose Monte Carlo (MC) code (e.g., MCNP) has been used in most treatment planning systems (TPS) to calculate dose distribution, which takes overmuch time in radiotherapy planning. Based on this, we developed COMPASS (COMpact PArticle Simulation System), an MC engine specifically for BNCT dose calculation. Several optimization algorithms are used in COMPASS to make it faster than general-purpose MC code. The parallel computation of COMPASS is performed by the message passing interface (MPI) library and OpenMP commands, which allows the user to increase computational speed by increasing the computer configurations. The physical dose of each voxel is calculated for developing a treatment plan. Comparison results show that the computed dose distribution of COMPASS is in good agreement with MCNP, and the computational efficiency is better than MCNP. These results validate that COMPASS has better performance than MCNP in BNCT dose calculation.
format Online
Article
Text
id pubmed-10366114
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-103661142023-07-26 Introduction to the Monte Carlo dose engine COMPASS for BNCT Zhong, Wan-Bing Chen, Jiang Teng, Yi-Chiao Liu, Yuan-Hao Sci Rep Article The Monte Carlo method is the most commonly used dose calculation method in the field of boron neutron capture therapy (BNCT). General-purpose Monte Carlo (MC) code (e.g., MCNP) has been used in most treatment planning systems (TPS) to calculate dose distribution, which takes overmuch time in radiotherapy planning. Based on this, we developed COMPASS (COMpact PArticle Simulation System), an MC engine specifically for BNCT dose calculation. Several optimization algorithms are used in COMPASS to make it faster than general-purpose MC code. The parallel computation of COMPASS is performed by the message passing interface (MPI) library and OpenMP commands, which allows the user to increase computational speed by increasing the computer configurations. The physical dose of each voxel is calculated for developing a treatment plan. Comparison results show that the computed dose distribution of COMPASS is in good agreement with MCNP, and the computational efficiency is better than MCNP. These results validate that COMPASS has better performance than MCNP in BNCT dose calculation. Nature Publishing Group UK 2023-07-24 /pmc/articles/PMC10366114/ /pubmed/37488142 http://dx.doi.org/10.1038/s41598-023-38648-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhong, Wan-Bing
Chen, Jiang
Teng, Yi-Chiao
Liu, Yuan-Hao
Introduction to the Monte Carlo dose engine COMPASS for BNCT
title Introduction to the Monte Carlo dose engine COMPASS for BNCT
title_full Introduction to the Monte Carlo dose engine COMPASS for BNCT
title_fullStr Introduction to the Monte Carlo dose engine COMPASS for BNCT
title_full_unstemmed Introduction to the Monte Carlo dose engine COMPASS for BNCT
title_short Introduction to the Monte Carlo dose engine COMPASS for BNCT
title_sort introduction to the monte carlo dose engine compass for bnct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366114/
https://www.ncbi.nlm.nih.gov/pubmed/37488142
http://dx.doi.org/10.1038/s41598-023-38648-y
work_keys_str_mv AT zhongwanbing introductiontothemontecarlodoseenginecompassforbnct
AT chenjiang introductiontothemontecarlodoseenginecompassforbnct
AT tengyichiao introductiontothemontecarlodoseenginecompassforbnct
AT liuyuanhao introductiontothemontecarlodoseenginecompassforbnct