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Introduction to the Monte Carlo dose engine COMPASS for BNCT
The Monte Carlo method is the most commonly used dose calculation method in the field of boron neutron capture therapy (BNCT). General-purpose Monte Carlo (MC) code (e.g., MCNP) has been used in most treatment planning systems (TPS) to calculate dose distribution, which takes overmuch time in radiot...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366114/ https://www.ncbi.nlm.nih.gov/pubmed/37488142 http://dx.doi.org/10.1038/s41598-023-38648-y |
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author | Zhong, Wan-Bing Chen, Jiang Teng, Yi-Chiao Liu, Yuan-Hao |
author_facet | Zhong, Wan-Bing Chen, Jiang Teng, Yi-Chiao Liu, Yuan-Hao |
author_sort | Zhong, Wan-Bing |
collection | PubMed |
description | The Monte Carlo method is the most commonly used dose calculation method in the field of boron neutron capture therapy (BNCT). General-purpose Monte Carlo (MC) code (e.g., MCNP) has been used in most treatment planning systems (TPS) to calculate dose distribution, which takes overmuch time in radiotherapy planning. Based on this, we developed COMPASS (COMpact PArticle Simulation System), an MC engine specifically for BNCT dose calculation. Several optimization algorithms are used in COMPASS to make it faster than general-purpose MC code. The parallel computation of COMPASS is performed by the message passing interface (MPI) library and OpenMP commands, which allows the user to increase computational speed by increasing the computer configurations. The physical dose of each voxel is calculated for developing a treatment plan. Comparison results show that the computed dose distribution of COMPASS is in good agreement with MCNP, and the computational efficiency is better than MCNP. These results validate that COMPASS has better performance than MCNP in BNCT dose calculation. |
format | Online Article Text |
id | pubmed-10366114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-103661142023-07-26 Introduction to the Monte Carlo dose engine COMPASS for BNCT Zhong, Wan-Bing Chen, Jiang Teng, Yi-Chiao Liu, Yuan-Hao Sci Rep Article The Monte Carlo method is the most commonly used dose calculation method in the field of boron neutron capture therapy (BNCT). General-purpose Monte Carlo (MC) code (e.g., MCNP) has been used in most treatment planning systems (TPS) to calculate dose distribution, which takes overmuch time in radiotherapy planning. Based on this, we developed COMPASS (COMpact PArticle Simulation System), an MC engine specifically for BNCT dose calculation. Several optimization algorithms are used in COMPASS to make it faster than general-purpose MC code. The parallel computation of COMPASS is performed by the message passing interface (MPI) library and OpenMP commands, which allows the user to increase computational speed by increasing the computer configurations. The physical dose of each voxel is calculated for developing a treatment plan. Comparison results show that the computed dose distribution of COMPASS is in good agreement with MCNP, and the computational efficiency is better than MCNP. These results validate that COMPASS has better performance than MCNP in BNCT dose calculation. Nature Publishing Group UK 2023-07-24 /pmc/articles/PMC10366114/ /pubmed/37488142 http://dx.doi.org/10.1038/s41598-023-38648-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Zhong, Wan-Bing Chen, Jiang Teng, Yi-Chiao Liu, Yuan-Hao Introduction to the Monte Carlo dose engine COMPASS for BNCT |
title | Introduction to the Monte Carlo dose engine COMPASS for BNCT |
title_full | Introduction to the Monte Carlo dose engine COMPASS for BNCT |
title_fullStr | Introduction to the Monte Carlo dose engine COMPASS for BNCT |
title_full_unstemmed | Introduction to the Monte Carlo dose engine COMPASS for BNCT |
title_short | Introduction to the Monte Carlo dose engine COMPASS for BNCT |
title_sort | introduction to the monte carlo dose engine compass for bnct |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366114/ https://www.ncbi.nlm.nih.gov/pubmed/37488142 http://dx.doi.org/10.1038/s41598-023-38648-y |
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