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Detection, visualization and quantification of protein complexes in human Alzheimer’s disease brains using proximity ligation assay
Examination of healthy and diseased human brain is essential to translational neuroscience. Protein–protein interactions play a pivotal role in physiological and pathological processes, but their detection is difficult, especially in aged and fixed human brain tissue. We used the in-situ proximity l...
Autores principales: | Romero-Fernandez, Wilber, Carvajal-Tapia, Cristian, Prusky, Alex, Katdare, Ketaki A., Wang, Emmeline, Shostak, Alena, Ventura-Antunes, Lissa, Harmsen, Hannah J., Lippmann, Ethan S., Fuxe, Kjell, MacGurn, Jason A., Borroto-Escuela, Dasiel O., Schrag, Matthew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366145/ https://www.ncbi.nlm.nih.gov/pubmed/37488165 http://dx.doi.org/10.1038/s41598-023-38000-4 |
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