Cargando…
Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy
Cancer progression is enhanced by the interaction of programmed death-ligand 1 (PDL1), which is associated with inhibition of the immune response against tumors, and vascular endothelial growth factor (VEGF), which inhibits immune cell activity while inducing angiogenesis and proliferation of cancer...
Autores principales: | Tzuri, Noam, Yegodayev, Ksenia M., Novoplansky, Ofra, Elkabets, Moshe, Aharoni, Amir, Papo, Niv |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366146/ https://www.ncbi.nlm.nih.gov/pubmed/37488176 http://dx.doi.org/10.1038/s41598-023-39076-8 |
Ejemplares similares
-
The Contribution of the Minimal Promoter Element to the Activity of Synthetic Promoters Mediating CAR Expression in the Tumor Microenvironment
por: Greenshpan, Yariv, et al.
Publicado: (2022) -
Production of scFv-Conjugated Affinity Silk Powder by Transgenic Silkworm Technology
por: Sato, Mitsuru, et al.
Publicado: (2012) -
Identification of Potent CD19 scFv for CAR T Cells through scFv Screening with NK/T-Cell Line
por: Kang, Chung Hyo, et al.
Publicado: (2020) -
scFv Antibody: Principles and Clinical Application
por: Ahmad, Zuhaida Asra, et al.
Publicado: (2012) -
Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv
por: Arslan, Merve, et al.
Publicado: (2022)