Cargando…

Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography

We aimed to obtain widefield (WF) swept source optical coherence tomography (SS-OCT) data and examine the features of choroidal thickness maps in healthy eyes. The posterior pole choroidal thickness was examined in 127 eyes using enhanced depth imaging of SS-OCT with a viewing angle of 20 (vertical)...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirano, Masatoshi, Muraoka, Yuki, Kogo, Takahiro, Ishikura, Masaharu, Nishigori, Naomi, Ueda-Arakawa, Naoko, Miyata, Manabu, Hata, Masayuki, Takahashi, Ayako, Miyake, Masahiro, Tsujikawa, Akitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366186/
https://www.ncbi.nlm.nih.gov/pubmed/37488140
http://dx.doi.org/10.1038/s41598-023-38845-9
_version_ 1785077114282704896
author Hirano, Masatoshi
Muraoka, Yuki
Kogo, Takahiro
Ishikura, Masaharu
Nishigori, Naomi
Ueda-Arakawa, Naoko
Miyata, Manabu
Hata, Masayuki
Takahashi, Ayako
Miyake, Masahiro
Tsujikawa, Akitaka
author_facet Hirano, Masatoshi
Muraoka, Yuki
Kogo, Takahiro
Ishikura, Masaharu
Nishigori, Naomi
Ueda-Arakawa, Naoko
Miyata, Manabu
Hata, Masayuki
Takahashi, Ayako
Miyake, Masahiro
Tsujikawa, Akitaka
author_sort Hirano, Masatoshi
collection PubMed
description We aimed to obtain widefield (WF) swept source optical coherence tomography (SS-OCT) data and examine the features of choroidal thickness maps in healthy eyes. The posterior pole choroidal thickness was examined in 127 eyes using enhanced depth imaging of SS-OCT with a viewing angle of 20 (vertical) × 23 (horizontal) mm, and choroidal thickness maps were generated. For SS-OCT image analysis, we developed a grid with inner and outer rings, each divided into superotemporal, inferotemporal, superonasal, and inferonasal quadrants, comprising a total of nine subfields, including the central 3-mm ring. The posterior pole choroidal thicknesses were significantly lower at the periphery than in the central area, in the inferior field than in the superior field, and in the nasal field than in the temporal field (p < 0.001 for all). We also evaluated the effects of age and axial length (AL) on the WF choroidal thickness. The choroidal thickness in all subfields was negatively associated with advanced age (p < 0.05). The choroidal thicknesses in the central and inferonasal inner and outer subfields were negatively associated with AL (p = 0.042, 0.034, and 0.022, respectively). These findings provide insights into the two-dimensional characteristics of choroidal thickness and its association with age and AL.
format Online
Article
Text
id pubmed-10366186
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-103661862023-07-26 Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography Hirano, Masatoshi Muraoka, Yuki Kogo, Takahiro Ishikura, Masaharu Nishigori, Naomi Ueda-Arakawa, Naoko Miyata, Manabu Hata, Masayuki Takahashi, Ayako Miyake, Masahiro Tsujikawa, Akitaka Sci Rep Article We aimed to obtain widefield (WF) swept source optical coherence tomography (SS-OCT) data and examine the features of choroidal thickness maps in healthy eyes. The posterior pole choroidal thickness was examined in 127 eyes using enhanced depth imaging of SS-OCT with a viewing angle of 20 (vertical) × 23 (horizontal) mm, and choroidal thickness maps were generated. For SS-OCT image analysis, we developed a grid with inner and outer rings, each divided into superotemporal, inferotemporal, superonasal, and inferonasal quadrants, comprising a total of nine subfields, including the central 3-mm ring. The posterior pole choroidal thicknesses were significantly lower at the periphery than in the central area, in the inferior field than in the superior field, and in the nasal field than in the temporal field (p < 0.001 for all). We also evaluated the effects of age and axial length (AL) on the WF choroidal thickness. The choroidal thickness in all subfields was negatively associated with advanced age (p < 0.05). The choroidal thicknesses in the central and inferonasal inner and outer subfields were negatively associated with AL (p = 0.042, 0.034, and 0.022, respectively). These findings provide insights into the two-dimensional characteristics of choroidal thickness and its association with age and AL. Nature Publishing Group UK 2023-07-24 /pmc/articles/PMC10366186/ /pubmed/37488140 http://dx.doi.org/10.1038/s41598-023-38845-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hirano, Masatoshi
Muraoka, Yuki
Kogo, Takahiro
Ishikura, Masaharu
Nishigori, Naomi
Ueda-Arakawa, Naoko
Miyata, Manabu
Hata, Masayuki
Takahashi, Ayako
Miyake, Masahiro
Tsujikawa, Akitaka
Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
title Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
title_full Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
title_fullStr Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
title_full_unstemmed Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
title_short Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
title_sort analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366186/
https://www.ncbi.nlm.nih.gov/pubmed/37488140
http://dx.doi.org/10.1038/s41598-023-38845-9
work_keys_str_mv AT hiranomasatoshi analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT muraokayuki analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT kogotakahiro analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT ishikuramasaharu analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT nishigorinaomi analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT uedaarakawanaoko analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT miyatamanabu analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT hatamasayuki analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT takahashiayako analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT miyakemasahiro analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography
AT tsujikawaakitaka analysisofwidefieldchoroidalthicknessmapsofhealthyeyesusingsweptsourceopticalcoherencetomography