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Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography
We aimed to obtain widefield (WF) swept source optical coherence tomography (SS-OCT) data and examine the features of choroidal thickness maps in healthy eyes. The posterior pole choroidal thickness was examined in 127 eyes using enhanced depth imaging of SS-OCT with a viewing angle of 20 (vertical)...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366186/ https://www.ncbi.nlm.nih.gov/pubmed/37488140 http://dx.doi.org/10.1038/s41598-023-38845-9 |
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author | Hirano, Masatoshi Muraoka, Yuki Kogo, Takahiro Ishikura, Masaharu Nishigori, Naomi Ueda-Arakawa, Naoko Miyata, Manabu Hata, Masayuki Takahashi, Ayako Miyake, Masahiro Tsujikawa, Akitaka |
author_facet | Hirano, Masatoshi Muraoka, Yuki Kogo, Takahiro Ishikura, Masaharu Nishigori, Naomi Ueda-Arakawa, Naoko Miyata, Manabu Hata, Masayuki Takahashi, Ayako Miyake, Masahiro Tsujikawa, Akitaka |
author_sort | Hirano, Masatoshi |
collection | PubMed |
description | We aimed to obtain widefield (WF) swept source optical coherence tomography (SS-OCT) data and examine the features of choroidal thickness maps in healthy eyes. The posterior pole choroidal thickness was examined in 127 eyes using enhanced depth imaging of SS-OCT with a viewing angle of 20 (vertical) × 23 (horizontal) mm, and choroidal thickness maps were generated. For SS-OCT image analysis, we developed a grid with inner and outer rings, each divided into superotemporal, inferotemporal, superonasal, and inferonasal quadrants, comprising a total of nine subfields, including the central 3-mm ring. The posterior pole choroidal thicknesses were significantly lower at the periphery than in the central area, in the inferior field than in the superior field, and in the nasal field than in the temporal field (p < 0.001 for all). We also evaluated the effects of age and axial length (AL) on the WF choroidal thickness. The choroidal thickness in all subfields was negatively associated with advanced age (p < 0.05). The choroidal thicknesses in the central and inferonasal inner and outer subfields were negatively associated with AL (p = 0.042, 0.034, and 0.022, respectively). These findings provide insights into the two-dimensional characteristics of choroidal thickness and its association with age and AL. |
format | Online Article Text |
id | pubmed-10366186 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-103661862023-07-26 Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography Hirano, Masatoshi Muraoka, Yuki Kogo, Takahiro Ishikura, Masaharu Nishigori, Naomi Ueda-Arakawa, Naoko Miyata, Manabu Hata, Masayuki Takahashi, Ayako Miyake, Masahiro Tsujikawa, Akitaka Sci Rep Article We aimed to obtain widefield (WF) swept source optical coherence tomography (SS-OCT) data and examine the features of choroidal thickness maps in healthy eyes. The posterior pole choroidal thickness was examined in 127 eyes using enhanced depth imaging of SS-OCT with a viewing angle of 20 (vertical) × 23 (horizontal) mm, and choroidal thickness maps were generated. For SS-OCT image analysis, we developed a grid with inner and outer rings, each divided into superotemporal, inferotemporal, superonasal, and inferonasal quadrants, comprising a total of nine subfields, including the central 3-mm ring. The posterior pole choroidal thicknesses were significantly lower at the periphery than in the central area, in the inferior field than in the superior field, and in the nasal field than in the temporal field (p < 0.001 for all). We also evaluated the effects of age and axial length (AL) on the WF choroidal thickness. The choroidal thickness in all subfields was negatively associated with advanced age (p < 0.05). The choroidal thicknesses in the central and inferonasal inner and outer subfields were negatively associated with AL (p = 0.042, 0.034, and 0.022, respectively). These findings provide insights into the two-dimensional characteristics of choroidal thickness and its association with age and AL. Nature Publishing Group UK 2023-07-24 /pmc/articles/PMC10366186/ /pubmed/37488140 http://dx.doi.org/10.1038/s41598-023-38845-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Hirano, Masatoshi Muraoka, Yuki Kogo, Takahiro Ishikura, Masaharu Nishigori, Naomi Ueda-Arakawa, Naoko Miyata, Manabu Hata, Masayuki Takahashi, Ayako Miyake, Masahiro Tsujikawa, Akitaka Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
title | Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
title_full | Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
title_fullStr | Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
title_full_unstemmed | Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
title_short | Analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
title_sort | analysis of widefield choroidal thickness maps of healthy eyes using swept source optical coherence tomography |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366186/ https://www.ncbi.nlm.nih.gov/pubmed/37488140 http://dx.doi.org/10.1038/s41598-023-38845-9 |
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