The Fe–S cluster assembly protein IscU2 increases α-ketoglutarate catabolism and DNA 5mC to promote tumor growth

IscU2 is a scaffold protein that is critical for the assembly of iron–sulfur (Fe–S) clusters and the functions of Fe–S-containing mitochondrial proteins. However, the role of IscU2 in tumor development remains unclear. Here, we demonstrated that IscU2 expression is much higher in human pancreatic du...

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Detalles Bibliográficos
Autores principales: Ren, Xiaojun, Yan, Jimei, Zhao, Qiongya, Bao, Xinzhu, Han, Xinyu, Zheng, Chen, Zhou, Yan, Chen, Lifang, Wang, Bo, Yang, Lina, Lin, Xi, Liu, Dandan, Lin, Yuyan, Li, Min, Fang, Hezhi, Lu, Zhimin, Lyu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366194/
https://www.ncbi.nlm.nih.gov/pubmed/37488138
http://dx.doi.org/10.1038/s41421-023-00558-8

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