Molecular basis of non-deletional HPFH in Thailand and identification of two novel mutations at the binding sites of CCAAT and GATA-1 transcription factors

High Hb F determinants are genetic defects associated with increased expression of hemoglobin F in adult life, classified as deletional and non-deletional forms. We report the first description of non-deletional hereditary persistence of fetal hemoglobin (HFPH) in Thailand. Study was done on 388 sub...

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Detalles Bibliográficos
Autores principales: Singha, Kritsada, Pansuwan, Anupong, Chewasateanchai, Mattanee, Fucharoen, Goonnapa, Fucharoen, Supan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366219/
https://www.ncbi.nlm.nih.gov/pubmed/37488161
http://dx.doi.org/10.1038/s41598-023-39173-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366219/
https://www.ncbi.nlm.nih.gov/pubmed/37488161
http://dx.doi.org/10.1038/s41598-023-39173-8

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