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Knockdown of protein interacting with C α kinase 1 aggravates sepsis-induced acute liver injury by regulating the TLR4/NF-κB pathway

Acute liver injury (ALI) may manifest at any phase of sepsis, yet an explicit therapeutic approach remains elusive. In this study, LPS and cecum ligation and puncture (CLP) were utilized to establish an inflammatory cell model and a murine model of sepsis-induced liver injury, respectively, aiming t...

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Detalles Bibliográficos
Autores principales: Wang, Huijun, Ma, Ting, Bao, Qianqian, Zhu, Lijun, Ying, Tingting, Yu, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366226/
https://www.ncbi.nlm.nih.gov/pubmed/37488153
http://dx.doi.org/10.1038/s41598-023-38852-w