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Rif1 Regulates Self-Renewal and Impedes Mesendodermal Differentiation of Mouse Embryonic Stem Cells

BACKGROUND: RAP1 interacting factor 1 (Rif1) is highly expressed in mice embryos and mouse embryonic stem cells (mESCs). It plays critical roles in telomere length homeostasis, DNA damage, DNA replication timing and ERV silencing. However, whether Rif1 regulates early differentiation of mESC is stil...

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Detalles Bibliográficos
Autores principales:	Liu, Cheng, Yu, Peng, Ren, Zongna, Yao, Fang, Wang, Li, Hu, Guang, Li, Pishun, Zhao, Quanyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366267/ https://www.ncbi.nlm.nih.gov/pubmed/36971904 http://dx.doi.org/10.1007/s12015-023-10525-1

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