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Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ
BACKGROUND: Different questionnaires assess self-reported medication adherence and others quantify aspects of patients attitudes towards medication, but not together in a single instrument. Gathering these two aspects in a single instrument could reduce patients survey burden. AIM: The aim of this s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366321/ https://www.ncbi.nlm.nih.gov/pubmed/37329432 http://dx.doi.org/10.1007/s11096-023-01612-x |
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author | Cabral, Ana C. Lavrador, Marta Castel-Branco, Margarida Figueiredo, Isabel Vitória Fernandez-Llimos, Fernando |
author_facet | Cabral, Ana C. Lavrador, Marta Castel-Branco, Margarida Figueiredo, Isabel Vitória Fernandez-Llimos, Fernando |
author_sort | Cabral, Ana C. |
collection | PubMed |
description | BACKGROUND: Different questionnaires assess self-reported medication adherence and others quantify aspects of patients attitudes towards medication, but not together in a single instrument. Gathering these two aspects in a single instrument could reduce patients survey burden. AIM: The aim of this study was to develop the Medication Adherence Universal Questionnaire (MAUQ) using the Maastricht Utrecht Adherence in Hypertension short version (MUAH-16) factorial structure as the hypothesized model. METHOD: A multistep process started with the modification of the MUAH-16 to obtain the MAUQ. Patients using at least one antihypertensive medicine were recruited. The two questionnaires, the MUAH-16 and MAUQ, were applied. A confirmatory factor analysis (CFA) was performed using the initial MUAH-16 s-order 4-factor model. An additional bifactor model with four uncorrelated factors and an overall score was tested. The comparative fit index (CFI), root mean square error of approximation (RMSEA) with confidence intervals (CIs), and standardized root mean squared residual (SRMR) were used to assess both models. RESULTS: A sample of 300 hypertensive patients completed the instruments. The CFA with the second-order 4-factor solution resulted in similar results for the MUAH-16 and MAUQ: CFIs of 0.934 and 0.930, RMSEAs of 0.043 [CI 0.030–0.056] and 0.045 [CI 0.031–0.057] and SRMRs of 0.060 and 0.061, respectively. The CFA with the bifactor model showed slightly better results for both the MUAH-16 and MAUQ: CFIs of 0.974 and 0.976, RMSEAs of 0.030 [CI 0.005–0.046] and 0.028 [CI 0.001–0.044], and SRMRs of 0.043 and 0.044, respectively. CONCLUSION: CFA demonstrated that the MAUQ presented a better fit to both models than the MUAH-16, obtaining a robust universal free instrument to assess medicine-taking behaviour and four medicine beliefs components. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11096-023-01612-x. |
format | Online Article Text |
id | pubmed-10366321 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-103663212023-07-26 Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ Cabral, Ana C. Lavrador, Marta Castel-Branco, Margarida Figueiredo, Isabel Vitória Fernandez-Llimos, Fernando Int J Clin Pharm Research Article BACKGROUND: Different questionnaires assess self-reported medication adherence and others quantify aspects of patients attitudes towards medication, but not together in a single instrument. Gathering these two aspects in a single instrument could reduce patients survey burden. AIM: The aim of this study was to develop the Medication Adherence Universal Questionnaire (MAUQ) using the Maastricht Utrecht Adherence in Hypertension short version (MUAH-16) factorial structure as the hypothesized model. METHOD: A multistep process started with the modification of the MUAH-16 to obtain the MAUQ. Patients using at least one antihypertensive medicine were recruited. The two questionnaires, the MUAH-16 and MAUQ, were applied. A confirmatory factor analysis (CFA) was performed using the initial MUAH-16 s-order 4-factor model. An additional bifactor model with four uncorrelated factors and an overall score was tested. The comparative fit index (CFI), root mean square error of approximation (RMSEA) with confidence intervals (CIs), and standardized root mean squared residual (SRMR) were used to assess both models. RESULTS: A sample of 300 hypertensive patients completed the instruments. The CFA with the second-order 4-factor solution resulted in similar results for the MUAH-16 and MAUQ: CFIs of 0.934 and 0.930, RMSEAs of 0.043 [CI 0.030–0.056] and 0.045 [CI 0.031–0.057] and SRMRs of 0.060 and 0.061, respectively. The CFA with the bifactor model showed slightly better results for both the MUAH-16 and MAUQ: CFIs of 0.974 and 0.976, RMSEAs of 0.030 [CI 0.005–0.046] and 0.028 [CI 0.001–0.044], and SRMRs of 0.043 and 0.044, respectively. CONCLUSION: CFA demonstrated that the MAUQ presented a better fit to both models than the MUAH-16, obtaining a robust universal free instrument to assess medicine-taking behaviour and four medicine beliefs components. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11096-023-01612-x. Springer International Publishing 2023-06-17 2023 /pmc/articles/PMC10366321/ /pubmed/37329432 http://dx.doi.org/10.1007/s11096-023-01612-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Article Cabral, Ana C. Lavrador, Marta Castel-Branco, Margarida Figueiredo, Isabel Vitória Fernandez-Llimos, Fernando Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ |
title | Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ |
title_full | Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ |
title_fullStr | Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ |
title_full_unstemmed | Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ |
title_short | Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ |
title_sort | development and validation of a medication adherence universal questionnaire: the mauq |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366321/ https://www.ncbi.nlm.nih.gov/pubmed/37329432 http://dx.doi.org/10.1007/s11096-023-01612-x |
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