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The APC-EPCR-PAR1 axis in sickle cell disease

Sickle Cell Disease (SCD) is a group of inherited hemoglobinopathies. Sickle cell anemia (SCA) is caused by a homozygous mutation in the β-globin generating sickle hemoglobin (HbS). Deoxygenation leads to pathologic polymerization of HbS and sickling of erythrocytes. The two predominant pathologies...

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Detalles Bibliográficos
Autores principales:	Ramadas, Nirupama, Sparkenbaugh, Erica M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366386/ https://www.ncbi.nlm.nih.gov/pubmed/37497271 http://dx.doi.org/10.3389/fmed.2023.1141020

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