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A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy

Spindle cell hemangioendothelioma (SCH) is extremely rare. Only four cases have been reported in the spinal cord (Mahdavi et al., 1996; Abdullah et al., 2002; Nasser et al., 2016; Talan-Hranilović et al., 2007) [1-4]. In addition to surgery, radiotherapy is another effective treatment for spinal cor...

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Autores principales: Yang, Jing, Li, Huimin, Gao, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366422/
https://www.ncbi.nlm.nih.gov/pubmed/37496923
http://dx.doi.org/10.1016/j.heliyon.2023.e18149
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author Yang, Jing
Li, Huimin
Gao, Jin
author_facet Yang, Jing
Li, Huimin
Gao, Jin
author_sort Yang, Jing
collection PubMed
description Spindle cell hemangioendothelioma (SCH) is extremely rare. Only four cases have been reported in the spinal cord (Mahdavi et al., 1996; Abdullah et al., 2002; Nasser et al., 2016; Talan-Hranilović et al., 2007) [1-4]. In addition to surgery, radiotherapy is another effective treatment for spinal cord SCH. Two patients received radiotherapy to a total dose of 50–55Gy and benefited from it. For the treatment of this benign tumor, no one has tried to lower the radiation dose so far. Description:We report a 56-year-old man with extramedullary subdural SCH located in the T10-T11 spinal cord. Low back pain and muscle weakness are the main manifestations. Postoperative follow-up MRI examinations were performed three months after surgery showed residual tumors, he subsequently received radiotherapy and benefited from it. We gave a radiation dose of 40Gy for the first time. The neurological symptoms completely returned to normal four months after radiotherapy, and no recurrence occurred in the follow-up of 24 months. Conclusion: Epidural lesions are more likely to occur in the upper segment of the thoracic spine for SCH. For patients with inoperable or residual surgery and deep tumors located in the functional area, radiotherapy can be used as the main treatment method. A total radiation dose of 40Gy could achieve good control of SCH and greatly reduce the probability of spinal cord injury.
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spelling pubmed-103664222023-07-26 A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy Yang, Jing Li, Huimin Gao, Jin Heliyon Case Report Spindle cell hemangioendothelioma (SCH) is extremely rare. Only four cases have been reported in the spinal cord (Mahdavi et al., 1996; Abdullah et al., 2002; Nasser et al., 2016; Talan-Hranilović et al., 2007) [1-4]. In addition to surgery, radiotherapy is another effective treatment for spinal cord SCH. Two patients received radiotherapy to a total dose of 50–55Gy and benefited from it. For the treatment of this benign tumor, no one has tried to lower the radiation dose so far. Description:We report a 56-year-old man with extramedullary subdural SCH located in the T10-T11 spinal cord. Low back pain and muscle weakness are the main manifestations. Postoperative follow-up MRI examinations were performed three months after surgery showed residual tumors, he subsequently received radiotherapy and benefited from it. We gave a radiation dose of 40Gy for the first time. The neurological symptoms completely returned to normal four months after radiotherapy, and no recurrence occurred in the follow-up of 24 months. Conclusion: Epidural lesions are more likely to occur in the upper segment of the thoracic spine for SCH. For patients with inoperable or residual surgery and deep tumors located in the functional area, radiotherapy can be used as the main treatment method. A total radiation dose of 40Gy could achieve good control of SCH and greatly reduce the probability of spinal cord injury. Elsevier 2023-07-11 /pmc/articles/PMC10366422/ /pubmed/37496923 http://dx.doi.org/10.1016/j.heliyon.2023.e18149 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yang, Jing
Li, Huimin
Gao, Jin
A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
title A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
title_full A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
title_fullStr A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
title_full_unstemmed A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
title_short A case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
title_sort case of extramedullary subdural spindle cell hemangioendothelioma of the thoracic spinal cord treated curatively with radiation therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366422/
https://www.ncbi.nlm.nih.gov/pubmed/37496923
http://dx.doi.org/10.1016/j.heliyon.2023.e18149
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