A contamination focused approach for optimizing the single-cell RNA-seq experiment

Droplet-based single-cell RNA-seq (scRNA-seq) data are plagued by ambient contaminations caused by nucleic acid material released by dead and dying cells. This material is mixed into the buffer and is co-encapsulated with cells, leading to a lower signal-to-noise ratio. Although there exist computat...

Descripción completa

Detalles Bibliográficos
Autores principales: Arceneaux, Deronisha, Chen, Zhengyi, Simmons, Alan J., Heiser, Cody N., Southard-Smith, Austin N., Brenan, Michael J., Yang, Yilin, Chen, Bob, Xu, Yanwen, Choi, Eunyoung, Campbell, Joshua D., Liu, Qi, Lau, Ken S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366499/
https://www.ncbi.nlm.nih.gov/pubmed/37496679
http://dx.doi.org/10.1016/j.isci.2023.107242

Ejemplares similares

Ejemplares similares