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DNA repair pathways-targeted cyclovirobuxine inhibits castration-resistant prostate cancer growth by promoting cell apoptosis and cycle arrest

BACKGROUND: Castration-resistant prostate cancer (CRPC) is a deadly malignancy without effective therapeutics. Cyclovirobuxine (CVB) can play an anticancer role by inhibiting mitochondrial function, regulating tumor cell apoptosis, dysregulating autophagy, and other mechanisms. This study aimed to e...

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Detalles Bibliográficos
Autores principales:	Gao, Ke, Zhu, Siying, Shao, Qiuju, Qi, Yuhong, Zhang, Chao, Li, Xiaoshun, Guo, Jiaheng, Wu, Guojun, Jiang, Hanbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366641/ https://www.ncbi.nlm.nih.gov/pubmed/37406549 http://dx.doi.org/10.1016/j.tranon.2023.101708

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