Selective HIF2A Inhibitors in the Management of Clear Cell Renal Cancer and Von Hippel–Lindau-Disease-Associated Tumors

Von Hippel–Lindau (VHL) loss is the hallmark event characterizing the clear cell renal cancer subtype (ccRCC). Carriers of germinal VHL mutations have an increased prevalence of kidney cysts and ccRCC as well as hemangioblastoma, pheochromocytoma and pancreatic neuroendocrine tumors. In both sporadi...

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Detalles Bibliográficos
Autores principales: Suárez, Cristina, Vieito, Maria, Valdivia, Augusto, González, Macarena, Carles, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366718/
https://www.ncbi.nlm.nih.gov/pubmed/37489462
http://dx.doi.org/10.3390/medsci11030046

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