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Visualization of Metastatic Lung Cancer with TiNIR

The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cell...

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Detalles Bibliográficos
Autores principales: Mun, Seul-Ki, Sim, Hyun Bo, Han, Ji Yeon, Kim, Hyeongyeong, Park, Dae-Han, Chang, Dong-Jo, Yee, Sung-Tae, Chang, Young-Tae, Kim, Jong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366764/
https://www.ncbi.nlm.nih.gov/pubmed/37489464
http://dx.doi.org/10.3390/tomography9040096
Descripción
Sumario:The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cells (TICs), with heme oxygenase 2 (HO2) as a promising therapeutic biomarker for tumor-initiating cells. In this study, TiNIR has demonstrated its effectiveness as an in vivo metastatic lung cancer tracker, highlighting its potential as a valuable tool in cancer research and therapy. The development of innovative approaches that selectively target metastatic cancers represents a promising avenue for improving survival rates and enhancing the quality of life of cancer patients.