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Visualization of Metastatic Lung Cancer with TiNIR

The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cell...

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Autores principales: Mun, Seul-Ki, Sim, Hyun Bo, Han, Ji Yeon, Kim, Hyeongyeong, Park, Dae-Han, Chang, Dong-Jo, Yee, Sung-Tae, Chang, Young-Tae, Kim, Jong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366764/
https://www.ncbi.nlm.nih.gov/pubmed/37489464
http://dx.doi.org/10.3390/tomography9040096
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author Mun, Seul-Ki
Sim, Hyun Bo
Han, Ji Yeon
Kim, Hyeongyeong
Park, Dae-Han
Chang, Dong-Jo
Yee, Sung-Tae
Chang, Young-Tae
Kim, Jong-Jin
author_facet Mun, Seul-Ki
Sim, Hyun Bo
Han, Ji Yeon
Kim, Hyeongyeong
Park, Dae-Han
Chang, Dong-Jo
Yee, Sung-Tae
Chang, Young-Tae
Kim, Jong-Jin
author_sort Mun, Seul-Ki
collection PubMed
description The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cells (TICs), with heme oxygenase 2 (HO2) as a promising therapeutic biomarker for tumor-initiating cells. In this study, TiNIR has demonstrated its effectiveness as an in vivo metastatic lung cancer tracker, highlighting its potential as a valuable tool in cancer research and therapy. The development of innovative approaches that selectively target metastatic cancers represents a promising avenue for improving survival rates and enhancing the quality of life of cancer patients.
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spelling pubmed-103667642023-07-26 Visualization of Metastatic Lung Cancer with TiNIR Mun, Seul-Ki Sim, Hyun Bo Han, Ji Yeon Kim, Hyeongyeong Park, Dae-Han Chang, Dong-Jo Yee, Sung-Tae Chang, Young-Tae Kim, Jong-Jin Tomography Communication The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cells (TICs), with heme oxygenase 2 (HO2) as a promising therapeutic biomarker for tumor-initiating cells. In this study, TiNIR has demonstrated its effectiveness as an in vivo metastatic lung cancer tracker, highlighting its potential as a valuable tool in cancer research and therapy. The development of innovative approaches that selectively target metastatic cancers represents a promising avenue for improving survival rates and enhancing the quality of life of cancer patients. MDPI 2023-06-21 /pmc/articles/PMC10366764/ /pubmed/37489464 http://dx.doi.org/10.3390/tomography9040096 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Mun, Seul-Ki
Sim, Hyun Bo
Han, Ji Yeon
Kim, Hyeongyeong
Park, Dae-Han
Chang, Dong-Jo
Yee, Sung-Tae
Chang, Young-Tae
Kim, Jong-Jin
Visualization of Metastatic Lung Cancer with TiNIR
title Visualization of Metastatic Lung Cancer with TiNIR
title_full Visualization of Metastatic Lung Cancer with TiNIR
title_fullStr Visualization of Metastatic Lung Cancer with TiNIR
title_full_unstemmed Visualization of Metastatic Lung Cancer with TiNIR
title_short Visualization of Metastatic Lung Cancer with TiNIR
title_sort visualization of metastatic lung cancer with tinir
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366764/
https://www.ncbi.nlm.nih.gov/pubmed/37489464
http://dx.doi.org/10.3390/tomography9040096
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