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Down-regulation of the alpha-2C adrenergic receptor: involvement of a serine/threonine motif in the third cytoplasmic loop

BACKGROUND: The mechanisms by which alpha-2 adrenergic receptors are down-regulated following chronic exposure to agonist are not well understood. Interestingly, the human alpha-2C receptor does not down-regulate, whereas the opossum alpha-2C receptor does down-regulate. A comparison of the amino ac...

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Detalles Bibliográficos
Autores principales: Deupree, Jean D, Borgeson, Claudia D, Bylund, David B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC103669/
https://www.ncbi.nlm.nih.gov/pubmed/11926967
http://dx.doi.org/10.1186/1471-2210-2-9