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Synthesis of Cyclopropanes via Hydrogen-Borrowing Catalysis

[Image: see text] Cyclopropanes are highly useful motifs that are often incorporated into drug candidates to improve potency, metabolic stability, or pharmacokinetic properties. An expedient method for the α-cyclopropanation of ketones using hydrogen borrowing (HB) catalysis is described. The transf...

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Detalles Bibliográficos
Autores principales:	Crompton, Jessica L., Frost, James R., Rowe, Sam M., Christensen, Kirsten E., Donohoe, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367074/ https://www.ncbi.nlm.nih.gov/pubmed/37428545 http://dx.doi.org/10.1021/acs.orglett.3c01768

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