Cargando…

The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing

OBJECTIVE: Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with a 5-year mortality rate of ~ 50%. New in vitro methods are needed for testing patients’ cancer cell response to anti-cancer treatments. We aimed to investigate how the gene expression of fresh carcinoma tissue...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hyytiäinen, Aini, Korelin, Katja, Toriseva, Mervi, Wilkman, Tommy, Kainulainen, Satu, Mesimäki, Karri, Routila, Johannes, Ventelä, Sami, Irjala, Heikki, Nees, Matthias, Al-Samadi, Ahmed, Salo, Tuula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367262/ https://www.ncbi.nlm.nih.gov/pubmed/37488620 http://dx.doi.org/10.1186/s12935-023-02982-y

Ejemplares similares

PCR-based zebrafish model for personalised medicine in head and neck cancer
por: Al-Samadi, Ahmed, et al.
Publicado: (2019)

Evaluation of in vitro and in vivo personalized cancer treatment assays for oral squamous cell carcinoma
por: Wahbi, Wafa, et al.
Publicado: (2023)

Epidemiological Study of p16 Incidence in Head and Neck Squamous Cell Carcinoma 2005–2015 in a Representative Northern European Population
por: Mylly, Mari, et al.
Publicado: (2022)

Cancer cell line microarray as a novel screening method for identification of radioresistance biomarkers in head and neck squamous cell carcinoma
por: Routila, Johannes, et al.
Publicado: (2021)

Angiogenesis Inhibitors for Head and Neck Squamous Cell Carcinoma Treatment: Is There Still Hope?
por: Hyytiäinen, Aini, et al.
Publicado: (2021)

Exposure to alcohol and overall survival in head and neck cancer: A regional cohort study
por: Denissoff, Alexander, et al.
Publicado: (2022)

Amphipathic barbiturates as marine product mimics with cytolytic and immunogenic effects on head and neck squamous cell carcinoma cell lines
por: von Hofsten, Susannah, et al.
Publicado: (2023)

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma
por: Tuomainen, Katja, et al.
Publicado: (2021)

Evaluation of prognostic biomarkers in a population-validated Finnish HNSCC patient cohort
por: Routila, J., et al.
Publicado: (2021)

Organotypic three-dimensional assays based on human leiomyoma–derived matrices
por: Salo, Tuula, et al.
Publicado: (2018)

Reliability of the pre-operative imaging to assess neck nodal involvement in oral cancer patients, a single-center study
por: Pakkanen, Antti L, et al.
Publicado: (2022)

Segmentation of Image Data from Complex Organotypic 3D Models of Cancer Tissues with Markov Random Fields
por: Robinson, Sean, et al.
Publicado: (2015)

A high-content image analysis approach for quantitative measurements of chemosensitivity in patient-derived tumor microtissues
por: Ahonen, Ilmari, et al.
Publicado: (2017)

Evaluation of the anticancer activity of RIN-1, a Notch signaling modulator, in head and neck squamous cell carcinoma
por: Czerwonka, Arkadiusz, et al.
Publicado: (2023)

Long-term quality of life after surgery of head and neck cancer with microvascular reconstruction: a prospective study with 4.9-years follow-up
por: Kainulainen, Satu, et al.
Publicado: (2019)

Recurrence of head and neck squamous cell carcinoma in relation to high-risk treatment volume
por: Nissi, Linda, et al.
Publicado: (2021)

T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence
por: Pakkanen, Pihla, et al.
Publicado: (2021)

In vitro models as tools for screening treatment options of head and neck cancer
por: Seliger, Barbara, et al.
Publicado: (2022)

Factors Affecting Intracellular Delivery and Release of Hydrophilic Versus Hydrophobic Cargo from Mesoporous Silica Nanoparticles on 2D and 3D Cell Cultures
por: Desai, Diti, et al.
Publicado: (2018)

Evaluation Challenges in the Validation of B7-H3 as Oral Tongue Cancer Prognosticator
por: Sieviläinen, Meri, et al.
Publicado: (2020)

Deep neck space infections: an upward trend and changing characteristics
por: Velhonoja, Jarno, et al.
Publicado: (2019)

Understanding the role of the R-spondin 2-LGR4 system in tongue squamous cell carcinoma progression
por: Al-Samadi, Ahmed, et al.
Publicado: (2019)

IDO1 Inhibition Reduces Immune Cell Exclusion Through Inducing Cell Migration While PD-1 Blockage Increases IL-6 and -8 Secretion From T Cells in Head and Neck Cancer
por: Sieviläinen, Meri, et al.
Publicado: (2022)

Emergency neck MRI: feasibility and diagnostic accuracy in cases of neck infection
por: Nurminen, Janne, et al.
Publicado: (2020)

Role of Cyclooxygenase-2 in Head and Neck Tumorigenesis
por: Frejborg, Ellen, et al.
Publicado: (2020)

Rapid prototyping modelling in oral and maxillofacial surgery: A two year retrospective study
por: Suomalainen, Anni, et al.
Publicado: (2015)

Vasculogenic Mimicry in Head and Neck Squamous Cell Carcinoma—Time to Take Notice
por: Salem, Abdelhakim, et al.
Publicado: (2021)

Dysphagia, hypothyroidism, and osteoradionecrosis after radiation therapy for head and neck cancer
por: Ranta, Pihla, et al.
Publicado: (2021)

Clinical and prognostic significance of emergency MRI findings in neck infections
por: Heikkinen, Jaakko, et al.
Publicado: (2021)

Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing
por: Tuomainen, Katja, et al.
Publicado: (2019)

Challenges in diagnosing head and neck cancer in primary health care
por: Nieminen, Markus, et al.
Publicado: (2020)

Human myoma tissue-based extracellular matrix models for testing the effects of irradiation on the HPV positive cells
por: Tuominen, Heidi, et al.
Publicado: (2020)

Variable roles of interleukin-17F in different cancers
por: Mikkola, Tiina, et al.
Publicado: (2022)

MRI of acute neck infections: evidence summary and pictorial review
por: Hirvonen, Jussi, et al.
Publicado: (2023)

Oral Microbiota—A New Frontier in the Pathogenesis and Management of Head and Neck Cancers
por: Metsäniitty, Marjut, et al.
Publicado: (2021)

Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models
por: Al-Samadi, Ahmed, et al.
Publicado: (2017)

Transcriptomic Profiling of JEG-3 cells using human leiomyoma derived matrix
por: Barmaki, Samineh, et al.
Publicado: (2022)

Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention
por: Åkerfelt, Malin, et al.
Publicado: (2015)

Comparative Analysis of Vascular Mimicry in Head and Neck Squamous Cell Carcinoma: In Vitro and In Vivo Approaches
por: Hujanen, Roosa, et al.
Publicado: (2021)

Magnetic resonance imaging findings in pediatric neck infections—a comparison with adult patients
por: Nurminen, Janne, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0pcom1pk7b08l3plpue62o8var