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Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China
OBJECTIVE: This study aimed to evaluate the associations between particulate matter (PM), lung function and Impulse Oscillometry System (IOS) parameters in chronic obstructive pulmonary disease (COPD) patients and identity effects between different regions in Beijing, China. METHODS: In this retrosp...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367330/ https://www.ncbi.nlm.nih.gov/pubmed/37488590 http://dx.doi.org/10.1186/s12889-023-16308-0 |
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author | Zhu, Rui-xia Nie, Xiu-hong Liu, Xiao-fang Zhang, Yong-xiang Chen, Jin Liu, Xue-jiao Hui, Xin-jie |
author_facet | Zhu, Rui-xia Nie, Xiu-hong Liu, Xiao-fang Zhang, Yong-xiang Chen, Jin Liu, Xue-jiao Hui, Xin-jie |
author_sort | Zhu, Rui-xia |
collection | PubMed |
description | OBJECTIVE: This study aimed to evaluate the associations between particulate matter (PM), lung function and Impulse Oscillometry System (IOS) parameters in chronic obstructive pulmonary disease (COPD) patients and identity effects between different regions in Beijing, China. METHODS: In this retrospective study, we recruited 1348 outpatients who visited hospitals between January 2016 and December 2019. Ambient air pollutant data were obtained from the central monitoring stations nearest the participants’ residential addresses. We analyzed the effect of particulate matter with aerodynamic diameter ≤ 2.5 μm (PM(2.5)) exposure on lung function and IOS parameters using a multiple linear regression model, adjusting for sex, smoking history, education level, age, body mass index (BMI), mean temperature, and relative humidity . RESULTS: The results showed a relationship between PM(2.5), lung function and IOS parameters. An increase of 10 µg/m(3) in PM(2.5) was associated with a decline of 2.083% (95% CI: −3.047 to − 1.103) in forced expiratory volume in one second /predict (FEV(1)%pred), a decline of 193 ml/s (95% CI: −258 to − 43) in peak expiratory flow (PEF), a decline of 0.932% (95% CI: −1.518 to − 0.342) in maximal mid-expiratory flow (MMEF); an increase of 0.732 Hz (95% CI: 0.313 to 1.148) in resonant frequency (F(res)), an increase of 36 kpa/(ml/s) (95% CI: 14 to 57) in impedance at 5 Hz (Z(5)) and an increase of 31 kpa/(ml/s) (95% CI: 2 to 54) in respiratory impedance at 5 Hz (R(5)). Compared to patients in the central district, those in the southern district had lower FEV(1)/FVC, FEV(1)%pred, PEF, FEF(75%), MMEF, X(5), and higher F(res), Z(5) and R(5) (p < 0.05). CONCLUSION: Short-term exposure to PM(2.5) was associated with reductions in lung function indices and an increase in IOS results in patients with COPD. The heavier the PM(2.5), the more severe of COPD. |
format | Online Article Text |
id | pubmed-10367330 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-103673302023-07-26 Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China Zhu, Rui-xia Nie, Xiu-hong Liu, Xiao-fang Zhang, Yong-xiang Chen, Jin Liu, Xue-jiao Hui, Xin-jie BMC Public Health Research OBJECTIVE: This study aimed to evaluate the associations between particulate matter (PM), lung function and Impulse Oscillometry System (IOS) parameters in chronic obstructive pulmonary disease (COPD) patients and identity effects between different regions in Beijing, China. METHODS: In this retrospective study, we recruited 1348 outpatients who visited hospitals between January 2016 and December 2019. Ambient air pollutant data were obtained from the central monitoring stations nearest the participants’ residential addresses. We analyzed the effect of particulate matter with aerodynamic diameter ≤ 2.5 μm (PM(2.5)) exposure on lung function and IOS parameters using a multiple linear regression model, adjusting for sex, smoking history, education level, age, body mass index (BMI), mean temperature, and relative humidity . RESULTS: The results showed a relationship between PM(2.5), lung function and IOS parameters. An increase of 10 µg/m(3) in PM(2.5) was associated with a decline of 2.083% (95% CI: −3.047 to − 1.103) in forced expiratory volume in one second /predict (FEV(1)%pred), a decline of 193 ml/s (95% CI: −258 to − 43) in peak expiratory flow (PEF), a decline of 0.932% (95% CI: −1.518 to − 0.342) in maximal mid-expiratory flow (MMEF); an increase of 0.732 Hz (95% CI: 0.313 to 1.148) in resonant frequency (F(res)), an increase of 36 kpa/(ml/s) (95% CI: 14 to 57) in impedance at 5 Hz (Z(5)) and an increase of 31 kpa/(ml/s) (95% CI: 2 to 54) in respiratory impedance at 5 Hz (R(5)). Compared to patients in the central district, those in the southern district had lower FEV(1)/FVC, FEV(1)%pred, PEF, FEF(75%), MMEF, X(5), and higher F(res), Z(5) and R(5) (p < 0.05). CONCLUSION: Short-term exposure to PM(2.5) was associated with reductions in lung function indices and an increase in IOS results in patients with COPD. The heavier the PM(2.5), the more severe of COPD. BioMed Central 2023-07-24 /pmc/articles/PMC10367330/ /pubmed/37488590 http://dx.doi.org/10.1186/s12889-023-16308-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Zhu, Rui-xia Nie, Xiu-hong Liu, Xiao-fang Zhang, Yong-xiang Chen, Jin Liu, Xue-jiao Hui, Xin-jie Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China |
title | Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China |
title_full | Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China |
title_fullStr | Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China |
title_full_unstemmed | Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China |
title_short | Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China |
title_sort | short-term effect of particulate matter on lung function and impulse oscillometry system (ios) parameters of chronic obstructive pulmonary disease (copd) in beijing, china |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367330/ https://www.ncbi.nlm.nih.gov/pubmed/37488590 http://dx.doi.org/10.1186/s12889-023-16308-0 |
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