Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study

Amyotrophic Lateral Sclerosis (ALS) is mainly characterized by the degeneration of corticospinal neurons and spinal α-motoneurons; vulnerable cells display prominent pTDP-43 inclusions. Evidence gathered from genetics, murine models, and iPSC-derived neurons point to the early involvement of synapse...

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Detalles Bibliográficos
Autores principales: Aousji, Oumayma, Feldengut, Simone, Antonucci, Stefano, Schön, Michael, Boeckers, Tobias M., Matschke, Jakob, Mawrin, Christian, Ludolph, Albert C., Del Tredici, Kelly, Roselli, Francesco, Braak, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367350/
https://www.ncbi.nlm.nih.gov/pubmed/37491361
http://dx.doi.org/10.1186/s40478-023-01616-8

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