Gallic acid and metformin co-administration reduce oxidative stress, apoptosis and inflammation via Fas/caspase-3 and NF-κB signaling pathways in thioacetamide-induced acute hepatic encephalopathy in rats

BACKGROUND: Hepatic encephalopathy (HE) is a consequence of chronic or acute liver diseases. This study evaluates the combined effect of gallic acid (GA), and metformin (Met) on the liver and brain damage associated with HE. METHODS: Acute HE was induced by a single dose of thioacetamide (TAA) (300 ...

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Detalles Bibliográficos
Autores principales: Mohamed, Ehsan Khedre, Hafez, Dawlat Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367384/
https://www.ncbi.nlm.nih.gov/pubmed/37491245
http://dx.doi.org/10.1186/s12906-023-04067-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367384/
https://www.ncbi.nlm.nih.gov/pubmed/37491245
http://dx.doi.org/10.1186/s12906-023-04067-9

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