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Current understanding of CTLA-4: from mechanism to autoimmune diseases

Autoimmune diseases (ADs) are characterized by the production of autoreactive lymphocytes, immune responses to self-antigens, and inflammation in related tissues and organs. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is majorly expressed in activated T cells and works as a critical regulator in the i...

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Detalles Bibliográficos
Autores principales: Hossen, Md Munnaf, Ma, Yanmei, Yin, Zhihua, Xia, Yuhao, Du, Jing, Huang, Jim Yi, Huang, Jennifer Jin, Zou, Linghua, Ye, Zhizhong, Huang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367421/
https://www.ncbi.nlm.nih.gov/pubmed/37497212
http://dx.doi.org/10.3389/fimmu.2023.1198365