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Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

BACKGROUND: Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome have been linked to genital inflammation, the molecular relat...

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Detalles Bibliográficos
Autores principales: Farr Zuend, Christina, Lamont, Alana, Noel-Romas, Laura, Knodel, Samantha, Birse, Kenzie, Kratzer, Kateryna, McQueen, Peter, Perner, Michelle, Ayele, Hossaena, Mutch, Sarah, Berard, Alicia R., Schellenberg, John J., Senturk, Faruk, McCorrister, Stuart, Westmacott, Garrett, Mulhall, Fran, Sandberg, Bonnie, Yu, Adelicia, Burnett, Margaret, Poliquin, Vanessa, Burgener, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367425/
https://www.ncbi.nlm.nih.gov/pubmed/37491398
http://dx.doi.org/10.1186/s40168-023-01594-y