Cargando…
DBF4 Dependent Kinase Inhibition Suppresses Hepatocellular Carcinoma Progression and Potentiates Anti-Programmed Cell Death-1 Therapy
The progression of hepatocellular carcinoma (HCC) remains a huge clinical challenge, and elucidation of the underlying molecular mechanisms is critical to develop effective therapeutic strategy. Dumbbell former 4 (DBF4) complexes with cell division cycle 7 (CDC7) to form DBF4-dependent kinase (DDK),...
Autores principales: | Zhang, Liang, Hong, Jiawei, Chen, Wei, Zhang, Wei, Liu, Xi, Lu, Jiahua, Tang, Hong, Yang, Zhentao, Zhou, Ke, Xie, Haiyang, Jia, Changku, Jiang, Donghai, Zheng, Shusen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367558/ https://www.ncbi.nlm.nih.gov/pubmed/37497004 http://dx.doi.org/10.7150/ijbs.80351 |
Ejemplares similares
-
Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase
por: Cheng, Jiaxuan, et al.
Publicado: (2022) -
Cdc7p-Dbf4p Regulates Mitotic Exit by Inhibiting Polo Kinase
por: Miller, Charles T., et al.
Publicado: (2009) -
Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei
por: Ma, Jiangtao, et al.
Publicado: (2010) -
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
por: Sheu, Yi-Jun, et al.
Publicado: (2010) -
Candida albicans Dbf4-dependent Cdc7 kinase plays a novel role in the inhibition of hyphal development
por: Lai, Wei-Chung, et al.
Publicado: (2016)