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ER stress activates TAp73α to promote colon cancer cell apoptosis via the PERK-ATF4 pathway

Colorectal cancer (CRC) is the fourth most diagnosed cancer worldwide. 43% of CRCs harbor p53 mutations. The tumor suppressor p53 induces cell growth arrest and/or apoptosis in response to stress, including endoplasmic reticulum (ER) stress. It has been documented that the p53 gene is mutated in mor...

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Detalles Bibliográficos
Autores principales:	Sun, Shengnan, Yi, Yong, Xiao, Zhi-Xiong Jim, Chen, Hu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367919/ https://www.ncbi.nlm.nih.gov/pubmed/37497416 http://dx.doi.org/10.7150/jca.84170

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