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Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands
There is increasing research on the potential application of diffuse optical spectroscopy and hyperspectral imaging for characterizing the health of the connective tissues, such as articular cartilage, during joint surgery. These optical techniques facilitate the rapid and objective diagnostic asses...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optica Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368039/ https://www.ncbi.nlm.nih.gov/pubmed/37497494 http://dx.doi.org/10.1364/BOE.488801 |
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author | Kafian-Attari, Iman Nippolainen, Ervin Bergmann, Florian Mirhashemi, Arash Paakkari, Petri Foschum, Florian Kienle, Alwin Töyräs, Juha Afara, Isaac O. |
author_facet | Kafian-Attari, Iman Nippolainen, Ervin Bergmann, Florian Mirhashemi, Arash Paakkari, Petri Foschum, Florian Kienle, Alwin Töyräs, Juha Afara, Isaac O. |
author_sort | Kafian-Attari, Iman |
collection | PubMed |
description | There is increasing research on the potential application of diffuse optical spectroscopy and hyperspectral imaging for characterizing the health of the connective tissues, such as articular cartilage, during joint surgery. These optical techniques facilitate the rapid and objective diagnostic assessment of the tissue, thus providing unprecedented information toward optimal treatment strategy. Adaption of optical techniques for diagnostic assessment of musculoskeletal disorders, including osteoarthritis, requires precise determination of the optical properties of connective tissues such as articular cartilage. As every indirect method of tissue optical properties estimation consists of a measurement step followed by a computational analysis step, there are parameters associated with these steps that could influence the estimated values of the optical properties. In this study, we report the absorption and reduced scattering coefficients of articular cartilage in the spectral band of 400-1400 nm. We assess the impact of the experimental setup parameters, including surrounding medium, sample volume, and scattering anisotropy factor on the reported optical properties. Our results suggest that the absorption coefficient of articular cartilage is sensitive to the variation in the surrounding medium, whereas its reduced scattering coefficient is invariant to the experimental setup parameters. |
format | Online Article Text |
id | pubmed-10368039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Optica Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-103680392023-07-26 Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands Kafian-Attari, Iman Nippolainen, Ervin Bergmann, Florian Mirhashemi, Arash Paakkari, Petri Foschum, Florian Kienle, Alwin Töyräs, Juha Afara, Isaac O. Biomed Opt Express Article There is increasing research on the potential application of diffuse optical spectroscopy and hyperspectral imaging for characterizing the health of the connective tissues, such as articular cartilage, during joint surgery. These optical techniques facilitate the rapid and objective diagnostic assessment of the tissue, thus providing unprecedented information toward optimal treatment strategy. Adaption of optical techniques for diagnostic assessment of musculoskeletal disorders, including osteoarthritis, requires precise determination of the optical properties of connective tissues such as articular cartilage. As every indirect method of tissue optical properties estimation consists of a measurement step followed by a computational analysis step, there are parameters associated with these steps that could influence the estimated values of the optical properties. In this study, we report the absorption and reduced scattering coefficients of articular cartilage in the spectral band of 400-1400 nm. We assess the impact of the experimental setup parameters, including surrounding medium, sample volume, and scattering anisotropy factor on the reported optical properties. Our results suggest that the absorption coefficient of articular cartilage is sensitive to the variation in the surrounding medium, whereas its reduced scattering coefficient is invariant to the experimental setup parameters. Optica Publishing Group 2023-06-15 /pmc/articles/PMC10368039/ /pubmed/37497494 http://dx.doi.org/10.1364/BOE.488801 Text en Published by Optica Publishing Group under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Kafian-Attari, Iman Nippolainen, Ervin Bergmann, Florian Mirhashemi, Arash Paakkari, Petri Foschum, Florian Kienle, Alwin Töyräs, Juha Afara, Isaac O. Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
title | Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
title_full | Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
title_fullStr | Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
title_full_unstemmed | Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
title_short | Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
title_sort | impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368039/ https://www.ncbi.nlm.nih.gov/pubmed/37497494 http://dx.doi.org/10.1364/BOE.488801 |
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