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Large-Scale CRISPR Screen of LDLR Pathogenic Variants

Familial hypercholesterolemia (FH) is a frequently occurring genetic disorder that is linked to early-onset cardiovascular disease. If left untreated, patients with this condition can develop severe cardiovascular complications. Unfortunately, many patients remain undiagnosed, and even when diagnose...

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Detalles Bibliográficos
Autores principales:	Li, Mengjing, Ma, Lerong, Chen, Yiwu, Li, Jianing, Wang, Yanbing, You, Wenni, Yuan, Hongming, Tang, Xiaochun, Ouyang, Hongsheng, Pang, Daxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAAS 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368174/ https://www.ncbi.nlm.nih.gov/pubmed/37496633 http://dx.doi.org/10.34133/research.0203

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